Production of steroid hormone and cyclic AMP in hybrids of adrenal and Leydig cells generated by electrofusion

Electrofusion of rat adrenal and Leydig cells generated hybrids capable of synthesizing simultaneously both testosterone and corticosterone, under stimulation of lutropin or adrenocorticotropin. Evidence was obtained indicating that under such circumstances, heterologous lutropin receptor—adrenal ad...

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Detalles Bibliográficos
Autores principales: Podesta, E.J., Solano, A.R., Molina Vedia, Y.L.
Formato: JOUR
Materias:
adenylate cyclase
corticosterone
corticotropin
cyclic amp
prolactin
testosterone
adrenal gland
animal cell
cell fusion
drug accumulation
drug tissue level
endocrine system
heredity
histology
in vitro study
leydig cell
male genital system
methodology
nonhuman
preliminary communication
priority journal
rat
Adrenal Glands
Animal
Cell Fusion
Corticosterone
Corticotropin
Cyclic AMP
Electricity
Hybrid Cells
Leydig Cells
Luteinizing Hormone
Male
Rats
Testosterone
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00142956_v145_n2_p329_Podesta
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Electrofusion of rat adrenal and Leydig cells generated hybrids capable of synthesizing simultaneously both testosterone and corticosterone, under stimulation of lutropin or adrenocorticotropin. Evidence was obtained indicating that under such circumstances, heterologous lutropin receptor—adrenal adenylate cyclase complexes were formed. Copyright © 1984, Wiley Blackwell. All rights reserved

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