Early effects of protein kinase modulators on DNA synthesis in rat cerebral cortex

By using tissue miniunits, protein kinase modulators, and topoisomerase inhibitors in short-term incubation (0-90 min) we studied (1) the role of protein phosphorylation in the immediate control of DNA replication in the developing rat cerebral cortex and (2) the mechanism of action for genistein- m...

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Detalles Bibliográficos
Autores principales: Yakisich, J.S., Sidén, A., Vargas, V.I., Eneroth, P., Cruz, M.
Formato: JOUR
Materias:
Cerebral cortex
DNA synthesis
Genistein
Protein kinases
Protein phosphorylation
Topoisomerases
calphostin C
camptothecin
DNA topoisomerase
DNA topoisomerase (ATP hydrolysing)
DNA topoisomerase inhibitor
etoposide
genistein
herbimycin A
phosphoprotein phosphatase inhibitor
protein kinase inhibitor
staurosporine
animal tissue
article
brain cortex
cell cycle S phase
controlled study
DNA replication
DNA synthesis inhibition
enzyme activity
enzyme inhibition
newborn
nonhuman
priority journal
protein phosphorylation
rat
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00144886_v159_n1_p164_Yakisich
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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