Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease

Congenital transmission of Trypanosoma cruzi may occur in some or all the gestations from a T. cruzi-infected mother. Variable rates of congenital transmission have been reported in different geographical areas where different parasitic strains predominate, suggesting that parasitic genotypes might...

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Detalles Bibliográficos
Autores principales: Burgos, J.M., Altcheh, J., Bisio, M., Duffy, T., Valadares, H.M.S., Seidenstein, M.E., Piccinali, R., Freitas, J.M., Levin, M.J., Macchi, L., Macedo, A.M., Freilij, H., Schijman, A.G.
Formato: JOUR
Materias:
Microsatellite loci
Phylogenetic lineage
Real time PCR
Transplacental transmission
Trypanosoma cruzi clonality
minicircle DNA
allele
blood
Chagas disease
disease transmission
genetic marker
genotype
molecular analysis
parasite transmission
phylogenetics
polymerase chain reaction
polymorphism
pregnancy
protozoan
adult
Argentina
article
blood sampling
Bolivia
child
congenital infection
controlled study
endemic disease
female
gene amplification
gene locus
genetic analysis
genetic line
human
infant
major clinical study
newborn
prevalence
restriction fragment length polymorphism
Trypanosoma
Trypanosoma cruzi
twins
vertical transmission
Adolescent
Adult
Animals
Chagas Disease
Child
Child, Preschool
Disease Susceptibility
Disease Transmission, Vertical
DNA, Protozoan
Female
Humans
Infant
Infant, Newborn
Male
Mothers
Polymerase Chain Reaction
Pregnancy
Pregnancy Complications, Parasitic
Risk Factors
South America
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00207519_v37_n12_p1319_Burgos
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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