TcPARP: A DNA damage-dependent poly(ADP-ribose) polymerase from Trypanosoma cruzi

Poly(ADP-ribose) polymerase (PARP) is a nuclear enzyme present in most eukaryotes and has been involved in processes such as DNA repair and gene expression. The poly(ADP-ribose) polymer (PAR) is mainly catabolised by poly(ADP-ribose) glycohydrolase. Here, we describe the cloning and characterisation...

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Detalles Bibliográficos
Autores principales: Fernández Villamil, S.H., Baltanás, R., Alonso, G.D., Vilchez Larrea, S.C., Torres, H.N., Flawiá, M.M.
Formato: JOUR
Materias:
DNA repair signalling
PARG
PARP
Trypanosoma cruzi
3 aminobenzamide
beta lapachone
histone
hydrogen peroxide
menadione
nicotinamide
nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase
theophylline
thymidine
clone
damage
DNA
enzyme activity
gene expression
inhibition
protozoan
recombination
article
catalysis
DNA damage
in vivo study
molecular cloning
nonhuman
nucleotide sequence
protein analysis
protein synthesis
sequence analysis
Animals
Base Sequence
Cloning, Molecular
DNA Damage
DNA Repair
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Escherichia coli
Gene Expression
Immunoblotting
Immunohistochemistry
Life Cycle Stages
Molecular Sequence Data
Parasitology
Poly Adenosine Diphosphate Ribose
Poly(ADP-ribose) Polymerases
Sequence Analysis, DNA
Eukaryota
Trypanosomatidae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00207519_v38_n3-4_p277_FernandezVillamil
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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