High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells

Beside the digestion of the extracellular matrix during tumor invasion and metastasis, more recently, new functions for matrix metalloproteinases (MMPs) have been proposed. We studied the expression and function of these enzymes in pituitary cells. We observed the activities of MMP-2 and MMP-9 toget...

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Detalles Bibliográficos
Autores principales: Pereda, M.P., Ledda, M.F., Goldberg, V., Chervín, A., Carrizo, G., Molina, H., Müller, A., Renner, U., Podhajcer, O., Arzt, E., Stalla, G.K.
Formato: JOUR
Materias:
batimastat
matrix metalloproteinase
adult
aged
article
cell proliferation
drug use
enzyme activity
female
growth regulation
human
hypophysis adenoma
hypophysis function
major clinical study
male
priority journal
Adenoma
Adult
Aged
Aged, 80 and over
Animals
Blotting, Northern
Cell Division
Female
Humans
Male
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Matrix Metalloproteinases
Middle Aged
Phenylalanine
Pituitary Gland
Pituitary Hormones
Pituitary Neoplasms
Protease Inhibitors
Rats
Thiophenes
Tissue Inhibitor of Metalloproteinase-1
Tissue Inhibitor of Metalloproteinase-2
Tumor Cells, Cultured
Tumor Stem Cells
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0021972X_v85_n1_p263_Pereda
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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