Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas

Curcumin (diferuloylmethane), a polyphenolic compound derived from the spice plant Curcuma longa, displays multiple actions on solid tumours including anti-angiogenic effects. Here we have studied in rodent and human pituitary tumour cells the influence of curcumin on the production of hypoxia induc...

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Detalles Bibliográficos
Autores principales:	Shan, B., Schaaf, C., Schmidt, A., Lucia, K., Buchfelder, M., Losa, M., Kuhlen, D., Kreutzer, J., Perone, M.J., Arzt, E., Stalla, G.K., Renner, U.
Formato:	JOUR
Materias:	curcumin hypoxia inducible factor 1alpha messenger RNA vasculotropin vasculotropin A adult aged angiogenesis animal cell article female human human cell hypophysis adenoma in vitro study male nonhuman priority journal protein secretion protein synthesis rat reverse transcription polymerase chain reaction Western blotting Adenoma Animals Antineoplastic Agents Cell Hypoxia Cell Line, Tumor Corticotrophs Curcumin Humans Hypoxia-Inducible Factor 1, alpha Subunit Lactotrophs Mice Neovascularization, Pathologic Pituitary Neoplasms Rats RNA, Messenger Somatotrophs Vascular Endothelial Growth Factor A
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00220795_v214_n3_p389_Shan
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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