Role of G-proteins in the effects of leptin on pedunculopontine nucleus neurons

The pedunculopontine nucleus (PPN), the cholinergic arm of the reticular activating system, regulates waking and rapid eye movement sleep. Here, we demonstrate immunohistochemical labeling of the leptin receptor signaling isoform in PPN neurons, and investigated the effects of G-protein modulation a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Beck, P., Mahaffey, S., Urbano, F.J., Garcia-Rill, E.
Formato: JOUR
Materias:
arousal
GDPβ, GTPγS
hyperpolarization-activated cation current
sodium current
guanine nucleotide binding protein
leptin
leptin receptor
n methyl dextro aspartic acid receptor
proton pump
sodium channel
animal cell
animal tissue
article
brain nerve cell
brain slice
brain stem
controlled study
female
male
nonhuman
patch clamp
pedunculopontine tegmental nucleus
priority journal
protein function
rat
Animals
Cyclic Nucleotide-Gated Cation Channels
Data Interpretation, Statistical
Excitatory Postsynaptic Potentials
Female
GTP-Binding Proteins
Immunohistochemistry
Leptin
Male
Membrane Potentials
Neurons
Patch-Clamp Techniques
Pedunculopontine Tegmental Nucleus
Population
Potassium Channels
Rats
Rats, Sprague-Dawley
Receptors, N-Methyl-D-Aspartate
Sodium Channels
Rattus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00223042_v126_n6_p705_Beck
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares