Isolation and structural elucidation of degradation products of alprazolam: Photostability studies of alprazolam tablets

Accelerated thermal, hydrolytic, and photochemical degradations of alprazolam were performed under several reaction conditions. The stress studies revealed the photolability of the drug as the most adverse stability factor; the main photodegradation products were isolated and properly characterized...

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Detalles Bibliográficos
Autores principales: Nudelman, N.S., Cabrera, C.G.
Formato: JOUR
Materias:
Alprazolam
Alprazolam photodegradation products
Alprazolam stability
Photochemical degradation
Triazolobenzodiazepines
alprazolam
aminoquinoline derivative
benzodiazepine derivative
benzophenone derivative
article
chemical reaction kinetics
drug degradation
drug isolation
drug stability
drug storage
hydrolysis
pH
photochemistry
structure analysis
tablet
thermostability
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00223549_v91_n5_p1274_Nudelman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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