Antioxidant properties in a non-polar environment of difluoromethyl bioisosteres of methyl hydroxycinnamates

Objectives Many natural antioxidants have poor pharmacokinetic properties that impair their therapeutic use. For hydroxycinnamic acids (HCAs) and other phenolic antioxidants, their major drawback is their low lipophilicity and a rapid metabolism. The difluoromethyl group may be considered as a '...

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Autores principales: Martínez, M.D., Luna, L., Tesio, A.Y., Feresin, G.E., Durán, F.J., Burton, G.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00223573_v68_n2_p233_Martinez
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