Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
The administration of leptin to leptin-deficient humans, and the analogous Lepob/Lepob mice, effectively reduces hyperphagia and obesity. But common obesity is associated with elevated leptin, which suggests that obese humans are resistant to this adipocyte hormone. In addition to regulating long-te...
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Autores principales: | , , , , , , , |
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Formato: | JOUR |
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Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00280836_v411_n6836_p480_Cowley |
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