Polysaccharides from Gracilaria corticata: Sulfation, chemical characterization and anti-HSV activities

In this study, we have analyzed water-extracted polysaccharides of Gracilaria corticata. The water extract (WE), a galactan-containing sub-fraction (F3) and their hyper sulfated derivatives (WES1, WES2, F3S1 and F3S2) had anti-HSV activity with inhibitory concentration 50% (IC50) from 1.1 to 27.4 μg...

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Detalles Bibliográficos
Autores principales:	Chattopadhyay, K., Ghosh, T., Pujol, C.A., Carlucci, M.J., Damonte, E.B., Ray, B.
Formato:	JOUR
Materias:	Anti-HSV activity Galactan sulfate Gracilaria corticata antivirus agent galactan Gracilaria corticata extract periodate polysaccharide unclassified drug animal cell anion exchange chromatography anticoagulation antiviral activity article controlled study drug structure drug sulfation gel permeation chromatography Gracilaria Herpes simplex virus 1 Herpes simplex virus 2 IC 50 matrix assisted laser desorption ionization time of flight mass spectrometry molecular weight nonhuman nuclear magnetic resonance spectroscopy Vero cell Animals Anticoagulants Antiviral Agents Cercopithecus aethiops Chromatography, Gel Complex Mixtures Galactans Herpesvirus 1, Human Herpesvirus 2, Human Hydrolysis Magnetic Resonance Spectroscopy Molecular Weight Oxidation-Reduction Periodic Acid Polysaccharides Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates Vero Cells Simplexvirus
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_01418130_v43_n4_p346_Chattopadhyay
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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