Nitric oxide modulation of the immune response against cholera toxin-adjuvated ovalbumin administered by the intranasal route

Here, we studied the effect of aminoguanidine (AG) treatment, a nitric oxide synthase (NOS)-2 inhibitor, during the immune response against intranasal administration of ovalbumin (OVA) mixed with cholera toxin (CT) in BALB/c mice. NOS-2 mRNA was detected by reverse transcription-PCR (RT-PCR) in samp...

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Autores principales: Gamba, G., Bonorino, P., Gonzalez-Videla, R., Benedetti, R., Cavalieri, H., Courreges, M.C., Massouh, E.J., Benencia, F.
Formato: JOUR
Materias:
Cholera toxin
Mucosal immunity
Nitric oxide
aminoguanidine
cholera toxin
immunoglobulin A
immunoglobulin G
immunoglobulin G1
immunoglobulin G2a
immunoglobulin M
nitric oxide
nitric oxide synthase inhibitor
ovalbumin
transforming growth factor beta
analytic method
animal cell
antigen specificity
article
controlled study
drug effect
drug inhibition
immune response
inoculation
male
mouse
mouse strain
mucosal immunity
nonhuman
priority journal
reverse transcription polymerase chain reaction
sampling
spleen cell
Administration, Intranasal
Animals
Cholera Toxin
Guanidines
Immunity, Cellular
Immunity, Mucosal
Lung
Mice
Nitric Oxide
Nitric Oxide Synthase
Ovalbumin
Transforming Growth Factor beta
Turbinates
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01652478_v92_n3_p245_Gamba
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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