Stressor predictability influences open field behavior, pain sensitivity and brain MAO inhibitory activity (tribulin) in the rat

The effects of predictable or unpredictable shocks on ambulation, pain sensitivity, plasma catecholamines and heart and brain monoamine oxidase (MAO) inhibitory activity were investigated in rats. Animals showed plasma catecholamines and heart MAO inhibitory activity sensitization irrespective of ty...

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Detalles Bibliográficos
Autores principales: Lemoine, A.P., Armando, I., Brun, J.C., Barontini, M., Segura, E.T.
Formato: JOUR
Materias:
Analgesia
Internal ambulation
Learned helplessness
Monoamine oxidase inhibitory activity
Stress
amine oxidase (flavin containing)
analgesia
animal experiment
animal tissue
article
brain tissue
catecholamine blood level
controlled study
heart
male
nonhuman
priority journal
rat
stress
Animal
Arousal
Brain
Catecholamines
Electroshock
Escape Reaction
Exploratory Behavior
Fear
Helplessness, Learned
Male
Mental Recall
Monoamine Oxidase
Monoamine Oxidase Inhibitors
Motor Activity
Pain Threshold
Rats
Rats, Sprague-Dawley
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01664328_v61_n1_p91_Lemoine
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:The effects of predictable or unpredictable shocks on ambulation, pain sensitivity, plasma catecholamines and heart and brain monoamine oxidase (MAO) inhibitory activity were investigated in rats. Animals showed plasma catecholamines and heart MAO inhibitory activity sensitization irrespective of type of treatment, while differences between groups were observed when open field and hot plate tests and brain MAO inhibitory activity were considered. These effects parallel those observed using the classic triadic design leading to the helpless state. Our results suggest that predictability per se is able to generate this phenomenon. © 1994.

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