TbVps15 is required for vesicular transport and cytokinesis in Trypanosoma brucei

The class III phosphatidylinositol 3-kinase (PI3K) Vps34 is an important regulator of key cellular functions, including cell growth, survival, intracellular trafficking, autophagy and nutrient sensing. In yeast, Vps34 is associated with the putative serine/threonine protein kinase Vps15, however, it...

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Detalles Bibliográficos
Autores principales: Schoijet, A.C., Miranda, K., Sternlieb, T., Barrera, N.M., Girard-Dias, W., de Souza, W., Alonso, G.D.
Formato: JOUR
Materias:
Cell cycle
Endocytosis
TbVps15 protein kinase
Trypanosoma brucei
concanavalin A
dextran
phosphatidylinositol 3 kinase
transferrin
protein binding
protein serine threonine kinase VPS15
animal cell
Article
cell growth
cell structure
cell vacuole
controlled study
cytokinesis
down regulation
endocytosis
enzyme activity
flagellum
growth inhibition
nonhuman
priority journal
protein expression
protein function
RNA interference
scanning electron microscopy
transmission electron microscopy
atomic force microscopy
cytology
disease transmission
enzymology
gene knockdown
genetics
metabolism
physiology
Trypanosoma brucei brucei
Class III Phosphatidylinositol 3-Kinases
Cytokinesis
Disease Transmission, Infectious
Gene Knockdown Techniques
Microscopy, Atomic Force
Microscopy, Electron, Transmission
Phosphatidylinositol 3-Kinase
Protein Binding
Vacuolar Sorting Protein VPS15
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01666851_v219_n_p33_Schoijet
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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