High level expression of bioactive recombinant human growth hormone in the milk of a cloned transgenic cow

Transgenic farm animals have been proposed as an alternative to current bioreactors for large scale production of biopharmaceuticals. However, the efficiency of both methods in the production of the same protein has not yet been established. Here we report the production of recombinant human growth...

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Detalles Bibliográficos
Autores principales: Salamone, D., Barañao, L., Santos, C., Bussmann, L., Artuso, J., Werning, C., Prync, A., Carbonetto, C., Dabsys, S., Munar, C., Salaberry, R., Berra, G., Berra, I., Fernández, N., Papouchado, M., Foti, M., Judewicz, N., Mujica, I., Muñoz, L., Alvarez, S.F., González, E., Zimmermann, J., Criscuolo, M., Melo, C.
Formato: JOUR
Materias:
Animal biotechnology
Recombinant hGH
Transgenic cloned cow
Biotechnology
Cost effectiveness
Dairy products
Drug products
Escherichia coli
Hormones
human growth hormone
animal cell
animal experiment
article
breed
cattle
clone
cost effectiveness analysis
cow
fertility
fetus
hematological parameters
hormone synthesis
milk
nonhuman
priority journal
progeny
transgenic animal
Animals
Animals, Genetically Modified
Cattle
Cloning, Organism
Human Growth Hormone
Humans
Milk Proteins
Recombinant Proteins
Animalia
Bos taurus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01681656_v124_n2_p469_Salamone
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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