Regional differences in veins wall viscosity, compliance, energetics and damping: Analysis of the pressure-diameter relationship during cyclical overloads

Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (WSt) a...

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Detalles Bibliográficos
Autores principales: Zócalo, Y., Santana, D.B., Lluberas, S., Armentano, R.L.
Formato: JOUR
Lenguaje:English
Materias:
Compliance
Damping
Energetic
Vascular physiology
Venous wall
Viscosity
animal tissue
article
bioenergy
biomechanics
blood vessel function
cava vein
femoral vein
jugular vein
mechanical stress
nonhuman
pressure volume curve
sheep
vein compliance
vein diameter
vein wall
venous circulation
viscosity
Animals
Biomechanics
Blood Pressure
Blood Volume
Femoral Vein
Jugular Veins
Sheep
Vena Cava, Inferior
Ovis aries
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07169760_v41_n2_p227_Zocalo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (WSt) and dissipated (WD) energy, damping (ξ), and their regional differences in order to evaluate their role in venous functioning during volume-pressure overloads. Methods: In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, WSt and ξ (at low and high P-D levels), η and WD were calculated. Results: For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η, WSt and WD (p<0.05), but not in ξ. Conclusion: The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher WSt and WD found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously.

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