Maternal chronic stress induces premature telencephalic vesicles development
Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the ef...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
| Aporte de: |
| id |
todo:paper_07179367_v24_n4_p525_Mugnaini |
|---|---|
| record_format |
dspace |
| spelling |
todo:paper_07179367_v24_n4_p525_Mugnaini2023-10-03T15:36:29Z Maternal chronic stress induces premature telencephalic vesicles development Mugnaini, M.T. Soñez, C.A. Rolando, A.N. Romanini, M.C. Bozzo, A.A. Pastorino, I.C. Gauna, H.F. Paz, D.A. Chronic stress Morphometric analysis Rats Telencephalic vesicle Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the effect of the chronic stress by immobilisation applied to pregnant rats over the forebrain development of the embryos. The morphometric analyses showed an accelerated evagination of the telencephalic vesicles in 12 days old fetus from stressed mothers. The forebrain perimeter and the thickness showed significative differences in relation to age-matched controls. This stress effect seemed reversible during subsequent gestational stages. This is the first work showing a transient acceleration in the development induced by the gestational stress. Our model provides a new tool for studying the effect of the stress on the development. © 2007 Sociedad Chilena de Anatom•br>. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Chronic stress Morphometric analysis Rats Telencephalic vesicle |
| spellingShingle |
Chronic stress Morphometric analysis Rats Telencephalic vesicle Mugnaini, M.T. Soñez, C.A. Rolando, A.N. Romanini, M.C. Bozzo, A.A. Pastorino, I.C. Gauna, H.F. Paz, D.A. Maternal chronic stress induces premature telencephalic vesicles development |
| topic_facet |
Chronic stress Morphometric analysis Rats Telencephalic vesicle |
| description |
Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the effect of the chronic stress by immobilisation applied to pregnant rats over the forebrain development of the embryos. The morphometric analyses showed an accelerated evagination of the telencephalic vesicles in 12 days old fetus from stressed mothers. The forebrain perimeter and the thickness showed significative differences in relation to age-matched controls. This stress effect seemed reversible during subsequent gestational stages. This is the first work showing a transient acceleration in the development induced by the gestational stress. Our model provides a new tool for studying the effect of the stress on the development. © 2007 Sociedad Chilena de Anatom•br>. |
| format |
JOUR |
| author |
Mugnaini, M.T. Soñez, C.A. Rolando, A.N. Romanini, M.C. Bozzo, A.A. Pastorino, I.C. Gauna, H.F. Paz, D.A. |
| author_facet |
Mugnaini, M.T. Soñez, C.A. Rolando, A.N. Romanini, M.C. Bozzo, A.A. Pastorino, I.C. Gauna, H.F. Paz, D.A. |
| author_sort |
Mugnaini, M.T. |
| title |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_short |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_full |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_fullStr |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_full_unstemmed |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_sort |
maternal chronic stress induces premature telencephalic vesicles development |
| url |
http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
| work_keys_str_mv |
AT mugnainimt maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT sonezca maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT rolandoan maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT romaninimc maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT bozzoaa maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT pastorinoic maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT gaunahf maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment AT pazda maternalchronicstressinducesprematuretelencephalicvesiclesdevelopment |
| _version_ |
1807320855008509952 |