Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi

Intracellular levels of cyclic nucleotide second messengers are regulated predominantly by a large superfamily of phosphodiesterases (PDEs). Trypanosoma cruzi, the causative agent of Chagas disease, encodes four different PDE families. One of these PDEs, T. cruzi PDE C2 (TcrPDEC2) has been character...

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Autores principales: Schoijet, A.C., Miranda, K., Medeiros, L.C.S., De Souza, W., Flawiá, M.M., Torres, H.N., Pignataro, O.P., Docampo, R., Alonso, G.D.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0950382X_v79_n1_p50_Schoijet
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