Effect of α lipoic acid amide on hexachlorobenzene porphyria

The aim of this work is to study the effect of thioctamide - the commercial form of a lipoic acid amide - on the porphyrinogenic action of hexachlorobenzene (HCB). For this purpose, porphyria was induced in rats by chronic HCB treatment, with or without simultaneous thioctamide administration. Two d...

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Detalles Bibliográficos
Autores principales:	Vilas, G.L., Aldonatti, C., San Martín De Viale, L.C., Del Ríos De Molina, M.C.
Formato:	JOUR
Materias:	α lipoic acid Free radical scavenger Hexachlorobenzene Lipid peroxidation Porphyria Thioctamide Uroporphyrinogen decarboxylase 5 aminolevulinate synthase amide aminolevulinic acid hexachlorobenzene porphobilinogen porphyrin scavenger thiobarbituric acid reactive substance thioctic acid uroporphyrin uroporphyrinogen decarboxylase animal experiment animal model article bioaccumulation controlled study enzyme activity excretion female liver nonhuman porphyria rat urine level Animals Female Free Radical Scavengers Porphyrias Rats Rats, Wistar Thioctic Acid Time Factors Animalia
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10399712_v47_n5_p815_Vilas
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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