N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes

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Oxidative stress plays a critical role in the pathogenesis of diabetes, hypertension and atherosclerosis. Some authors reported that fat accumulation correlates to systemic oxidative stress in humans and mice, but the relationship of lipid production and oxidative metabolism is still unclear. In our...

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Detalles Bibliográficos
Autores principales: Calzadilla, P., Sapochnik, D., Cosentino, S., Diz, V., Dicelio, L., Calvo, J.C., Guerra, L.N.
Formato: JOUR
Materias:
Adipocyte differentiation
NAC
Triglyceride
acetylcysteine
beta actin
CCAAT enhancer binding protein
copper zinc superoxide dismutase
glutathione peroxidase
glutathione peroxidase 1
insulin receptor
manganese superoxide dismutase
metallothionein
peroxisome proliferator activated receptor gamma
protein kinase B
reactive oxygen metabolite
somatomedin C
superoxide dismutase
triacylglycerol
biological marker
CCAAT enhancer binding protein beta
glutathione
adipocyte
aerobic metabolism
article
cell culture
cell differentiation
concentration response
controlled study
culture medium
DNA content
down regulation
enzyme activity
enzyme assay
human
human cell
lipid peroxidation
lipid storage
low drug dose
obesity
oxidative stress
protein content
protein expression
protein phosphorylation
Western blotting
3T3 cell line
animal
cytology
metabolism
mouse
Mus
3T3-L1 Cells
Acetylcysteine
Adipocytes
Animals
Biological Markers
CCAAT-Enhancer-Binding Protein-beta
Cell Differentiation
Glutathione
Glutathione Peroxidase
Mice
PPAR gamma
Reactive Oxygen Species
Superoxide Dismutase
Triglycerides
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14220067_v12_n10_p6936_Calzadilla
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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