Involvement of leptin in the molecular physiology of the placenta

Leptin is a homeostatic regulator in the placenta where it promotes proliferation, protein synthesis and the expression of tolerogenic maternal response molecules such as HLA-G. Leptin also exerts an anti-apoptotic action in placenta controlling the expression of p53 master cell cycle regulator unde...

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Detalles Bibliográficos
Autores principales: Schanton, M., Maymó, J.L., Pérez-Pérez, A., Sánchez-Margalet, V., Varone, C.L.
Formato: JOUR
Materias:
cyclic AMP dependent protein kinase
DNA
estrogen
histone
leptin
placental peptide hormone
protein p53
transcription factor
transcription factor Sp1
Article
cell differentiation
cell proliferation
cell survival
disease predisposition
DNA methylation
epigenetics
histone acetylation
homeostasis
human
metabolic disorder
molecular biology
nuclear reprogramming
placenta
preeclampsia
pregnancy
pregnancy diabetes mellitus
priority journal
promoter region
protein expression
protein function
protein induction
protein modification
regulatory mechanism
signal transduction
spontaneous abortion
trophoblast
uterus
animal
cytology
female
metabolism
physiology
Animals
Female
Humans
Leptin
Placenta
Pregnancy
Signal Transduction
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14701626_v155_n1_pR1_Schanton
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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