Male cytogenetic evaluation prior to assisted reproduction procedures performed in Mar del Plata, Argentina
Objective: This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal semen parameters. Methods: the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral...
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| Autores principales: | , , , , , , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_15175693_v20_n2_p62_Poli |
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| Sumario: | Objective: This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal semen parameters. Methods: the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral blood through chromosome banding techniques before assisted reproduction procedures. Results: In this series of 141 infertile men, 19 (13%) had chromosomal anomalies and 35 (25%) had polymorphic variants. The main chromosome abnormalities were reciprocal translocations and marker chromosomes in mosaic. Conclusions: These results stress the relevance of cytogenetic studies for infertile males as a diagnostic tool and a valuable input in genetic counseling. © 2016, Sociedade Brasileira de Reproducao Assistida. All right reserved. |
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