Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity

FK506-binding proteins are members of the immunophilin family of proteins. Those immunophilins associated to the 90-kDa-heat-shock protein, Hsp90, have been proposed as potential modulators of signalling cascade factors chaperoned by Hsp90. FKBP51 and FKBP52 are the best characterized Hsp90-bound im...

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Detalles Bibliográficos
Autores principales: Lagadari, M., Zgajnar, N.R., Gallo, L.I., Galigniana, M.D.
Formato: JOUR
Materias:
FKBP51
FKBP52
Hsp90
hTERT
Immunophilin
Telomerase
fk 506 binding protein
fk 506 binding protein 51
fk 506 binding protein 52
heat shock protein 90
peroxide
proteasome
radicicol
reactive oxygen metabolite
telomerase
telomerase reverse transcriptase
unclassified drug
protein binding
tacrolimus binding protein 5
algorithm
Article
cancer cell
cell fractionation
cell nucleus
cell survival
cellular distribution
confocal microscopy
controlled study
cytoplasm
enzyme activity
fibroblast
gene overexpression
genetic background
human
human cell
immunofluorescence
immunoprecipitation
interphase
mitochondrion
oxidative stress
priority journal
protein localization
quantitative analysis
Western blotting
metabolism
protein degradation
tumor cell line
Cell Line, Tumor
Cell Nucleus
Cell Survival
HSP90 Heat-Shock Proteins
Humans
Mitochondria
Oxidative Stress
Proteasome Endopeptidase Complex
Protein Binding
Proteolysis
Tacrolimus Binding Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15747891_v10_n7_p1086_Lagadari
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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