Phytochemical Study of the Genus Salpichroa (Solanaceae), Chemotaxonomic Considerations, and Biological Evaluation in Prostate and Breast Cancer Cells

Twelve Salpichroa taxa have been phytochemically analyzed. From the aerial parts of S. scandens, four known salpichrolides A, C, I, S, and an unreported withanolide named salpichrolide V (1), were isolated. In S. dependens, S. gayi, S. glandulosa subsp. glandulosa, S. glandulosa subps. weddellii, S....

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Detalles Bibliográficos
Autores principales: Basso, A.V., Leiva González, S., Barboza, G.E., Careaga, V.P., Calvo, J.C., Sacca, P.A., Nicotra, V.E.
Formato: JOUR
Materias:
Chemotaxonomic markers
Cytotoxic activities
Salpichroa
Structure elucidation
Withanolides
2,3 dihydrosalpicrolide b
antineoplastic agent
doxorubicin
plant medicinal product
salpichrolide a
salpichrolide c
salpichrolide d
salpichrolide g
salpichrolide m
salpichrolide s
salpichrolide t
salpichrolide v
unclassified drug
antineoplastic activity
Article
breast cancer
cancer cell
cancer chemotherapy
cell density
chemotaxonomy
column chromatography
comparative study
controlled study
cytotoxicity
drug isolation
heteronuclear multiple bond correlation
heteronuclear single quantum coherence
human
human cell
in vitro study
nuclear Overhauser effect
prostate carcinoma
proton nuclear magnetic resonance
Salpichroa dependens
Salpichroa gayi
Salpichroa glandulosa
Salpichroa leucantha
Salpichroa micrantha
Salpichroa microloba
Salpichroa proboscidea
Salpichroa ramosissima
Salpichroa scandens
Salpichroa tristis
Salpichroa weberbauerii
Solanaceae
thin layer chromatography
ultraviolet spectrophotometry
breast tumor
cell survival
chemistry
drug effects
drug screening
female
isolation and purification
male
MCF-7 cell line
metabolism
pathology
prostate tumor
tumor cell line
Breast Neoplasms
Cell Line, Tumor
Cell Survival
Chromatography, Thin Layer
Drug Screening Assays, Antitumor
Female
Humans
Male
MCF-7 Cells
Phytochemicals
Prostatic Neoplasms
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_16121872_v14_n8_p_Basso
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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