Metallated porphyrin-doped conjugated polymer nanoparticles for efficient photodynamic therapy of brain and colorectal tumor cells

Aim: Assess biocompatibility, uptake and photodynamic therapy (PDT) mechanism of metallated porphyrin doped conjugated polymer nanoparticles (CPNs) in human brain and colorectal tumor cells and macrophages. Materials & methods: CPNs were developed employing 9,9-dioctylfluorene-alt-benzothiadiazo...

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Detalles Bibliográficos
Autores principales:	Ibarra, L.E., Porcal, G.V., Macor, L.P., Ponzio, R.A., Spada, R.M., Lorente, C., Chesta, C.A., Rivarola, V.A., Palacios, R.E.
Formato:	JOUR
Materias:	apoptosis brain tumor colorectal tumor conjugated polymer nanoparticles metallated porphyrin photodynamic therapy ROS conjugated polymer nanoparticle metalloporphyrin nanoparticle unclassified drug Article biocompatibility brain tumor cell line cell damage cell killing cell membrane cellular distribution colorectal cancer cell line controlled study cytotoxicity drug mechanism human human cell in vitro study lysosome macrophage oxidative stress photochemistry priority journal RAW 264.7 cell line SW480 cell line T98G cell line
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_17435889_v13_n6_p605_Ibarra
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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