Characterization of the B-Raf interactome in mouse hippocampal neuronal cells

B-Raf links a variety of extracellular stimuli downstream of cell surface receptors, constituting a determining factor in the ability of neurons to activate ERK. A detailed study of the B-Raf interactome is necessary to clarify the intricacy of B-Raf-dependent signal transduction. We used a mouse hi...

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Detalles Bibliográficos
Autores principales: Bonfiglio, J.J., Maccarrone, G., Rewerts, C., Holsboer, F., Arzt, E., Turck, C.W., Silberstein, S.
Formato: JOUR
Materias:
B-Raf
Interactome
Mass spectrometry
Neurons
Proteomics
B Raf kinase
cell surface receptor
chaperone
mitogen activated protein kinase
amino acid sequence
animal cell
article
enzyme activation
enzyme regulation
gel electrophoresis
hippocampus
matrix assisted laser desorption ionization time of flight mass spectrometry
mouse
nerve cell
nonhuman
priority journal
protein analysis
protein expression
protein interaction
proteomics
RNA metabolism
RNA translation
signal transduction
Animals
Blotting, Western
Cells, Cultured
Chromatography, Liquid
Cytoskeleton
Electrophoresis, Gel, Two-Dimensional
Hippocampus
Mice
Molecular Chaperones
Proto-Oncogene Proteins B-raf
RNA, Messenger
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_18743919_v74_n2_p186_Bonfiglio
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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