hypothesis article 22 nonhuman 20 Animals 18 controlled study 14 priority journal 14 animal cell 10 Humans 8 human 8 inhibition kinetics 8 mouse 8 Animalia 6 Cell Line, Tumor 6 Memory 6 Mice 6 NF-kappa B 6 Signal Transduction 6 cancer cell culture 6 enzyme activity 6 enzyme inhibition 6 immunoglobulin enhancer binding protein 6 long term memory 6 male 6 protein phosphorylation 6 1-Phosphatidylinositol 3-Kinase 4 Akt 4 Analysis of Variance 4 Apoptosis 4 Cell Death 4 Dose-Response Relationship, Drug 4