major clinical study human 354 female 258 male 254 adult 248 article 244 Humans 224 controlled study 220 priority journal 210 Female 198 Male 198 Adult 152 Middle Aged 126 aged 118 Argentina 108 Aged 90 Article 78 adolescent 72 child 66 Adolescent 64 Child 48 middle aged 48 Human 44 nonhuman 40 human cell 36 risk factor 34 Child, Preschool 32 human tissue 32 Aged, 80 and over 30 genotype 30