regulatory mechanism nonhuman 192 priority journal 182 article 176 controlled study 162 Animals 138 human 112 Humans 104 unclassified drug 96 animal cell 78 protein expression 78 human cell 70 protein function 70 animal experiment 58 metabolism 58 signal transduction 58 enzyme activity 52 mouse 52 Female 46 Mice 44 female 44 messenger RNA 44 animal 40 male 38 animal tissue 36 Article 34 gene expression 34 rat 34 Signal Transduction 32 physiology 32