Initiation of glycogen biosynthesis in Escherichia coli studies of the properties of the enzymes involved

The properties of the enzymes involved in the initiation of glycogen biosynthesis in Escherichia coli were studied. It was found that the enzymic activities which transfer the glycosyl residues from UDPglucose or ADPglucose for the glucoprotein synthesis had differing stabilities upon storage at 4°C...

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Autor principal: Barengo, R.
Otros Autores: Krisman, C.R
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1978
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
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024 7 |2 scopus  |a 2-s2.0-0018181202 
024 7 |2 cas  |a glycogen, 9005-79-2; Adenosine Diphosphate Glucose, 2140-58-1; Glucosyltransferases, EC 2.4.1.-; Glycogen Synthase, EC 2.4.1.11; Glycogen, 9005-79-2; Uridine Diphosphate Glucose, 133-89-1 
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100 1 |a Barengo, R. 
245 1 0 |a Initiation of glycogen biosynthesis in Escherichia coli studies of the properties of the enzymes involved 
260 |c 1978 
270 1 0 |m Barengo, R.; Instituto de Investigaciones Bioquimicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Krisman, (1972) Biochem. Biophys. Res. Commun., 46, pp. 1202-1212 
504 |a Krisman, Barengo, (1975) Eur. J. Biochem., 52, pp. 117-123 
504 |a Butler, Lee, Whelan, (1977) Carbohydr. Res., 55, pp. 73-82 
504 |a Barengo, Flawiá, Krisman, (1975) FEBS Lett., 53, pp. 274-278 
504 |a Krebs, Preiss, (1975) MTP International Review of Sciences — Biochemistry of Carbohydrates — Biochemistry Series One, 5, pp. 337-389. , 5th edn., W.J. Whelan, Butterworths-University Park Press, London 
504 |a Wright, Robbins, (1965) Biochim. Biophys. Acta, 104, pp. 594-596 
504 |a Recondo, Dankert, Leloir, Isolation of adenosine diphosphate D-glucose from corn graiws (1965) Biochemical and Biophysical Research Communications, 12, pp. 204-207 
504 |a Lowry, Rosebrough, Farr, Randall, (1961) J. Biol. Chem., 193, pp. 265-275 
504 |a Krisman, (1962) Anal. Biochem., 4, pp. 17-23 
504 |a Barengo, Krisman, (1976) Acta Physiol. Latinoamer., 26, pp. 289-296 
504 |a Lavintman, Tandecarz, Carceller, Mendiara, Cardini, (1974) Eur. J. Biochem., 50, pp. 145-155 
504 |a Fontana, Krisman, (1978) Biochim. Biophys. Acta, 540, pp. 183-189 
504 |a Ward, Wright, Cell-Wall Synthesis in Dictyostelium discoideum. I. In Vitro Synthesis from Uridine Diphosphoglucose* (1965) Biochemistry, 4, pp. 2021-2026 
504 |a Gunja-Smith, Patil, Smith, (1977) J. Bacteriol., 130, pp. 818-825 
520 3 |a The properties of the enzymes involved in the initiation of glycogen biosynthesis in Escherichia coli were studied. It was found that the enzymic activities which transfer the glycosyl residues from UDPglucose or ADPglucose for the glucoprotein synthesis had differing stabilities upon storage at 4°C. The small amount of glycogen and the saccharide firmly bound to the membrane preparation, were degraded during the storage period. The activity measured in fresh and in stored preparations gave different time dependence curves. The stored preparation had a lag period which could be due to the transfer of the first glucose units to the protein. Both UDPglucose and ADPglucose: protein glucosyltransferases were affected in different ways by detergents. Based on the results presented, it may be concluded that both enzymatic activities are due to different enzymes. Furthermore, both enzymatic activities are different from that which transfers glucose from ADPglucose to glycogen. The following mechanism for the de novo synthesis is suggested. Glycogen in E. coli could be initiated by two different enzymes which transfer glucose to a protein acceptor either from UDPglucose or ADPglucose. Once the saccharide linked to the protein has reached a certain size it is almost exclusively enlarged by another ADPglucose-dependent enzyme. The participation of branching enzyme will produce a polysaccharide with the characteristics of glycogen. © 1978.  |l eng 
593 |a Instituto de Investigaciones Bioquimicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490, 1428 Buenos Aires, Argentina 
690 1 0 |a GLYCOGEN 
690 1 0 |a ADENOSINE DIPHOSPHATE GLUCOSE:PROTEIN GLUCOSYLTRANSFERASE 
690 1 0 |a ANIMAL EXPERIMENT 
690 1 0 |a ESCHERICHIA COLI 
690 1 0 |a IN VITRO STUDY 
690 1 0 |a URIDINE DIPHOSPHATE GLUCOSE:PROTEIN GLUCOSYLTRANSFERASE 
690 1 0 |a ADENOSINE DIPHOSPHATE GLUCOSE 
690 1 0 |a ESCHERICHIA COLI 
690 1 0 |a GLUCOSYLTRANSFERASES 
690 1 0 |a GLYCOGEN 
690 1 0 |a GLYCOGEN SYNTHASE 
690 1 0 |a KINETICS 
690 1 0 |a SUBSTRATE SPECIFICITY 
690 1 0 |a URIDINE DIPHOSPHATE GLUCOSE 
700 1 |a Krisman, C.R. 
773 0 |d 1978  |g v. 540  |h pp. 190-196  |k n. 2  |p Biochim. Biophys. Acta Gen. Subj.  |x 03044165  |w (AR-BaUEN)CENRE-2260  |t BBA - General Subjects 
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856 4 0 |u https://hdl.handle.net/20.500.12110/paper_03044165_v540_n2_p190_Barengo  |y Handle 
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