Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin
Twenty-one-day-old Wistar rats were fed a diet containing 0.6% cuprizone for 2 weeks. Studies carried out after withdrawal of cuprizone showed histological evidences of marked demyelination in the corpus callosum. Biochemical studies of isolated myelin showed a marked decrease in myelin proteins, ph...
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2006
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 13170caa a22015257a 4500 | ||
|---|---|---|---|
| 001 | PAPER-21841 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518205320.0 | ||
| 008 | 190411s2006 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-33645729410 | |
| 024 | 7 | |2 cas |a broxuridine, 59-14-3; cuprizone, 370-81-0; galactosylceramide, 85305-88-0; Antigens; Antigens, CD11b; Apoproteins; apotransferrin; Bromodeoxyuridine, 59-14-3; chondroitin sulfate proteoglycan 4; Cuprizone, 370-81-0; Cytoskeletal Proteins; DAPI, 47165-04-8; Galactolipids; Glial Fibrillary Acidic Protein; Indoles; Myelin Basic Proteins; Proteoglycans; Transferrin, 11096-37-0 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a EXNEA | ||
| 100 | 1 | |a Adamo, A.M. | |
| 245 | 1 | 0 | |a Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin |
| 260 | |c 2006 | ||
| 270 | 1 | 0 | |m Soto, E.F.; Instituto de Química y Físicoquímica Biológica (IQUIFIB), UBA-CONICET, Departamento de Química Biológica, Buenos Aires, C1113AAD, Argentina; email: edufsoto@mail.retina.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Armstrong, R.C., Le, T.Q., Frost, E.E., Borke, R.C., Vana, A.C., Absence of fibroblast growth factor 2 promotes oligodendroglial repopulation of demyelinated white matter (2002) J. Neurosci., 22, pp. 8574-8585 | ||
| 504 | |a Arnett, H.A., Mason, J., Marino, M., Suzuki, K., Matsushima, G.K., Ting, J.P.-Y., TNFα promotes proliferation of oligodendrocyte progenitors and remyelination (2001) Nat. Neurosci., 4, pp. 1116-1122 | ||
| 504 | |a Blakemore, W.F., Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone (1973) J. Neurol. Sci., 20, pp. 63-72 | ||
| 504 | |a Blakemore, W.F., Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone (1974) J. Neurol. Sci., 22, pp. 121-127 | ||
| 504 | |a Cammer, W., The neurotoxicant, cuprizone, retards the differentiation of oligodendrocytes in vitro (1999) J. Neurol. Sci., 168, pp. 116-120 | ||
| 504 | |a Cammer, W., Zhang, H., Atypical localization of the oligodendrocytic isoform (PI) of glutathion-S-transferase in astrocytes during cuprizone intoxication (1993) J. Neurosci. Res., 36, pp. 183-190 | ||
| 504 | |a Carlton, W.W., Spongiform encephalopathy induced in rats and guinea pigs by cuprizone (1969) Exp. Mol. Pathol., 10, pp. 274-287 | ||
| 504 | |a Casella, G.T.B., Bartlett Bunge, M., Wood, P.M., Improved immunocytochemical identification of neural, endothelial, and inflammatory cell types in paraffin-embedded injured adult rat spinal cord (2004) J. Neurosci. Methods, 139, pp. 1-11 | ||
| 504 | |a Chen, P.S., Toribara, T., Warner, H., Microdetermination of phosphorus (1956) Anal. Chem., 28, pp. 1756-1758 | ||
| 504 | |a Escobar Cabrera, O.E., Bongarzone, E.R., Soto, E.F., Pasquini, J.M., Single intracerebral injection of apotransferrin in young rats induces increased myelination (1994) Dev. Neurosci., 16, pp. 248-254 | ||
| 504 | |a Escobar Cabrera, O.E., Zakin, M.M., Soto, E.F., Pasquini, J.M., Single intracranial injection of apotransferrin in young rats increases the expression of specific myelin protein mRNA (1997) J. Neurosci. Res., 47, pp. 603-608 | ||
| 504 | |a Escobar Cabrera, O.E., Bongiovanni, G., Hallak, M., Soto, E.F., Pasquini, J.M., The cytoskeletal components of the myelin fraction are affected by a single intracranial injection of apotransferrin in young rats (2000) Neurochem. Res., 25, pp. 669-676 | ||
| 504 | |a Espinosa de los Monteros, A., Peña, L.A., de Vellis, J., Does transferrin have a special role in the nervous system (1989) J. Neurosci. Res., 24, pp. 125-136 | ||
| 504 | |a Espinosa de los Monteros, A., Kumar, S., Zhao, P., Huang, C.J., Nazarian, R., Pan, T., Scully, S., de Vellis, J., Transferrin is an essential factor for myelination (1999) Neurochem. Res., 24, pp. 235-248 | ||
| 504 | |a Espinosa-Jeffrey, A., Kumar, S., Zhao, P.M., Awosika, O., Agbo, C., Huang, A., Chang, R., De Vellis, J., Transferrin regulates transcription of the MBP gene and its action synergizes with IGF-1 to enhance myelinogenesis in the md rat (2002) Dev. Neurosci., 24, pp. 227-241 | ||
| 504 | |a Folch, J., Lees, M., Sloane Stanley, G.H., A simple method for the isolation and purification of total lipides from animal tissues (1957) J. Biol. Chem., 226, pp. 497-509 | ||
| 504 | |a Garcia, C.I., Paez, P., Soto, E.F., Pasquini, J.M., Differential effect of apotransferrin on two populations of oligodendroglial cells (2003) Glia, 42, pp. 406-416 | ||
| 504 | |a Hess, H.H., Lewin, E., Microassay of Biochemical structural components in nervous tissues: II. Methods for cerebrosides, proteolipid proteins and residue proteins (1965) J. Neurochem., 12, pp. 205-211 | ||
| 504 | |a Komoly, S., Jeyasingham, M.D., Pratt, O.E., Lantos, P.L., Decrease in oligodendrocyte carbonic anhydrase activity preceding myelin degeneration in cuprizone induced demyelination (1987) J. Neurol. Sci., 79, pp. 141-148 | ||
| 504 | |a Lapetina, E., Soto, E.F., de Robertis, E., Lipids and proteolipids in isolated subcellular membranes of rat brain cortex (1968) J. Neurochem., 15, pp. 437-445 | ||
| 504 | |a Love, S., Cuprizone neurotoxicity in the rat: morphologic observations (1988) J. Neurol. Sci., 84, pp. 223-237 | ||
| 504 | |a Lowry, D.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., Protein measurement with the Folin phenol reagent (1951) J. Biol. Chem., 193, pp. 265-275 | ||
| 504 | |a Ludwin, S.K., Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity (1978) Lab. Invest., 39, pp. 597-612 | ||
| 504 | |a Ludwin, S., Central nervous system remyelination studies in chronically damaged tissue (1994) Ann. Neurol., 36, pp. 143-145. , (Suppl.) | ||
| 504 | |a Marta, C.B., Escobar Cabrera, O.E., Garcia, C.I., Villar, M.J., Pasquini, J.M., Soto, E.F., Oligodendroglial cell differentiation in rat brain is accelerated by the intracranial injection of apotransferrin (2000) Cell. Mol. Biol., 46, pp. 529-539 | ||
| 504 | |a Marta, C.B., Paez, P., Lopez, M., Pellegrino de Iraldi, A., Soto, E.F., Pasquini, J.M., Morphological changes of myelin sheaths in rats intracranially injected with apotransferrin (2003) Neurochem. Res., 28, pp. 101-110 | ||
| 504 | |a Mason, J.L., Toews, A., Hoststtler, J.D., Morell, P., Suzuki, K., Goldman, J.E., Matsushima, G.K., Oligodendrocytes and progenitors become progressively depleted with chronically demyelinated lesions (2004) Am. J. Pathol., 164, pp. 1673-1682 | ||
| 504 | |a Matsushima, G.K., Morell, P., The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system (2001) Brain Pathol., 11, pp. 107-116 | ||
| 504 | |a Muse, E.D., Jurevics, H., Toews, A.D., Matsushima, G.K., Morell, P., Parameters related to lipid metabolism as markers of myelination in mouse brain (2001) J. Neurochem., 76, pp. 77-86 | ||
| 504 | |a Norton, W.T., Poduslo, S.E., Myelination in rat brain: method of myelin isolation (1973) J. Neurochem., 21, pp. 749-757 | ||
| 504 | |a Oberhammer, F., Fritsch, G., Schmied, M., Pavelka, M., Printz, D., Purchio, T., Lassmann, H., Schulte-Hermann, R., Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease (1993) J. Cell. Sci., 104, pp. 66-73 | ||
| 504 | |a Paez, P.M., Marta, C.B., Moreno, M.B., Soto, E.F., Pasquini, J.M., Apotransferrin decreases migration and enhances differentiation of oligodendroglial progenitor cells in an in vitro system (2002) Dev. Neurosci., 24, pp. 47-58 | ||
| 504 | |a Paez, P.M., García, C.I., Davio, C., Campagnoni, A.T., Soto, E.F., Pasquini, J.M., Apotransferrin promotes the differentiation of two oligodendroglial cell lines (2004) Glia, 46, pp. 207-217 | ||
| 504 | |a Saleh, M.C., Espinosa de los Monteros, A., de Arriba Zerpa, G.A., Fontaine, I., Piaud, O., Djordjijevic, D., Baroukh, N., Guillou, F., Myelination and motor coordination are increased in transferrin transgenic mice (2003) J. Neurosci. Res., 72, pp. 587-594 | ||
| 504 | |a Suzuki, K., Kikkawa, Y., Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone) (1969) Am. J. Pathol., 54, pp. 307-325 | ||
| 520 | 3 | |a Twenty-one-day-old Wistar rats were fed a diet containing 0.6% cuprizone for 2 weeks. Studies carried out after withdrawal of cuprizone showed histological evidences of marked demyelination in the corpus callosum. Biochemical studies of isolated myelin showed a marked decrease in myelin proteins, phospholipids, and galactocerebrosides as well as a marked decrease in myelin yield. Treatment of these animals with a single intracranial injection of 350 ng of apotransferrin at the time of withdrawal of cuprizone induced a marked increase in myelin deposition resulting in a significantly improved remyelination, evaluated by histological, immunocytochemical, and biochemical parameters, in comparison to what was observed in spontaneous recovery. Immunocytochemical studies of cryotome sections to analyze developmental parameters of the oligodendroglial cell population at the time of termination of cuprizone and at different times thereafter showed that in the untreated animals, there was a marked increase in the number of NG2-BrdU-positive precursor cells together with a marked decrease in MBP expression at the peak of cuprizone-induced demyelination. As expected, the amount of precursor cells decreased markedly during spontaneous remyelination and was accompanied by an increase in MBP reactivity. In the apotransferrin-treated animals, these phenomena occurred much faster, and remyelination was much more efficient than in the untreated controls. The results of this study suggest that apotransferrin is a very active promyelinating agent which could be important for the treatment of certain demyelinating conditions. © 2006 Elsevier Inc. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: This work has been supported by Grant 092 from the University of Buenos Aires. | ||
| 593 | |a Instituto de Química y Físicoquímica Biológica (IQUIFIB), UBA-CONICET, Departamento de Química Biológica, Buenos Aires, C1113AAD, Argentina | ||
| 690 | 1 | 0 | |a APOTRANSFERRIN |
| 690 | 1 | 0 | |a CUPRIZONE |
| 690 | 1 | 0 | |a DEMYELINATING DISEASES |
| 690 | 1 | 0 | |a DEMYELINATION |
| 690 | 1 | 0 | |a OLIGODENDROGLIAL CELL DIFFERENTIATION |
| 690 | 1 | 0 | |a REMYELINATION |
| 690 | 1 | 0 | |a APOTRANSFERRIN |
| 690 | 1 | 0 | |a BROXURIDINE |
| 690 | 1 | 0 | |a CUPRIZONE |
| 690 | 1 | 0 | |a GALACTOSYLCERAMIDE |
| 690 | 1 | 0 | |a MYELIN PROTEIN |
| 690 | 1 | 0 | |a PHOSPHOLIPID |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CHEMICAL ANALYSIS |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CORPUS CALLOSUM |
| 690 | 1 | 0 | |a DEMYELINATING DISEASE |
| 690 | 1 | 0 | |a DEMYELINATION |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HISTOLOGY |
| 690 | 1 | 0 | |a IMMUNOCYTOCHEMISTRY |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN EXPRESSION |
| 690 | 1 | 0 | |a PROTEIN ISOLATION |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a REMYELINIZATION |
| 690 | 1 | 0 | |a STATISTICAL SIGNIFICANCE |
| 690 | 1 | 0 | |a STEM CELL |
| 690 | 1 | 0 | |a ANALYSIS OF VARIANCE |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a ANIMALS, NEWBORN |
| 690 | 1 | 0 | |a ANTIGENS |
| 690 | 1 | 0 | |a ANTIGENS, CD11B |
| 690 | 1 | 0 | |a APOPROTEINS |
| 690 | 1 | 0 | |a BRAIN |
| 690 | 1 | 0 | |a BROMODEOXYURIDINE |
| 690 | 1 | 0 | |a CELL COUNT |
| 690 | 1 | 0 | |a CUPRIZONE |
| 690 | 1 | 0 | |a CYTOSKELETAL PROTEINS |
| 690 | 1 | 0 | |a DEMYELINATING DISEASES |
| 690 | 1 | 0 | |a DRUG INTERACTIONS |
| 690 | 1 | 0 | |a GALACTOLIPIDS |
| 690 | 1 | 0 | |a GLIAL FIBRILLARY ACIDIC PROTEIN |
| 690 | 1 | 0 | |a IMMUNOHISTOCHEMISTRY |
| 690 | 1 | 0 | |a MYELIN BASIC PROTEINS |
| 690 | 1 | 0 | |a MYELIN SHEATH |
| 690 | 1 | 0 | |a PROTEOGLYCANS |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, WISTAR |
| 690 | 1 | 0 | |a RECOVERY OF FUNCTION |
| 690 | 1 | 0 | |a REGENERATION |
| 690 | 1 | 0 | |a TIME FACTORS |
| 690 | 1 | 0 | |a TRANSFERRIN |
| 650 | 1 | 7 | |2 spines |a INDOLES |
| 700 | 1 | |a Paez, P.M. | |
| 700 | 1 | |a Escobar Cabrera, O.E. | |
| 700 | 1 | |a Wolfson, M. | |
| 700 | 1 | |a Franco, P.G. | |
| 700 | 1 | |a Pasquini, J.M. | |
| 700 | 1 | |a Soto, E.F. | |
| 773 | 0 | |d 2006 |g v. 198 |h pp. 519-529 |k n. 2 |p Exp. Neurol. |x 00144886 |w (AR-BaUEN)CENRE-4716 |t Experimental Neurology | |
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| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00144886_v198_n2_p519_Adamo |y Handle |
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