Striped, bioactive Ce-TiO2 materials with peroxynitrite- scavenging activity

Controlling aligned fiber micro-architectures to simulate the extracellular matrix for inducing important biological functions is a key challenge with regard to successful tissue regeneration. Here we present a bottom-up microemulsion-mediated strategy to obtain highly bioactive and biocompatible, s...

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Autor principal: Gravina, A.N
Otros Autores: Ruso, J.M, Laiuppa, J.A, Santillán, G.E, Marco-Brown, J.L, D'Elia, N.L, Messina, P.V
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2014
Acceso en línea:Registro en Scopus
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100 1 |a Gravina, A.N. 
245 1 0 |a Striped, bioactive Ce-TiO2 materials with peroxynitrite- scavenging activity 
260 |c 2014 
270 1 0 |m Messina, P.V.; Department of Chemistry, INQUISUR-CONICET, Universidad Nacional Del sur, 8000, Bahía Blanca, Argentina; email: pmessina@uns.edu.ar 
506 |2 openaire  |e Política editorial 
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520 3 |a Controlling aligned fiber micro-architectures to simulate the extracellular matrix for inducing important biological functions is a key challenge with regard to successful tissue regeneration. Here we present a bottom-up microemulsion-mediated strategy to obtain highly bioactive and biocompatible, striped Ce-TiO2 nano-crystalline superstructures with ONOO - scavenging activity. The employment of a bulkier organic ceria precursor in the material synthesis has several concurrent effects: (I) influencing the interfacial microemulsion droplet elasticity to create an aligned distribution of prismatic anatase nanoparticles causing the final lined morphology, (II) stabilizing the anatase active phase in a fine dispersed state and improving its resistance to the thermal anatase-rutile conversion, (III) indirectly favoring the rapid formation on the material surface of a hydroxyapatite layer composed of sphere-like globules of 3-5 μm in diameter essential for bone-bonding, and finally (IV) accelerating the ONOO- degradation into less harmful species NO2- and O 2. © The 2014 Royal Society of Chemistry.  |l eng 
593 |a Department of Chemistry, INQUISUR-CONICET, Universidad Nacional Del sur, 8000, Bahía Blanca, Argentina 
593 |a Soft Matter and Molecular Biophysics Group, Department of Applied Physics, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain 
593 |a Department of Biology, Biochemistry and Pharmacy, Universidad Nacional Del sur, 8000, Bahía Blanca, Argentina 
593 |a Department of Inorganic Chemistry, Analytics and Physical Chemistry, INQUIMAE, Universidad de Buenos Aires, Pabellón II, Buenos Aires, C1428EHA, Argentina 
690 1 0 |a ANATASE NANOPARTICLES 
690 1 0 |a BIOLOGICAL FUNCTIONS 
690 1 0 |a EXTRACELLULAR MATRICES 
690 1 0 |a HYDROXYAPATITE LAYERS 
690 1 0 |a MATERIAL SURFACE 
690 1 0 |a MATERIAL SYNTHESIS 
690 1 0 |a MICRO ARCHITECTURES 
690 1 0 |a SCAVENGING ACTIVITIES 
690 1 0 |a BIOCOMPATIBILITY 
690 1 0 |a ELASTICITY 
690 1 0 |a MICROEMULSIONS 
690 1 0 |a OXIDE MINERALS 
690 1 0 |a SYNTHESIS (CHEMICAL) 
690 1 0 |a TITANIUM DIOXIDE 
700 1 |a Ruso, J.M. 
700 1 |a Laiuppa, J.A. 
700 1 |a Santillán, G.E. 
700 1 |a Marco-Brown, J.L. 
700 1 |a D'Elia, N.L. 
700 1 |a Messina, P.V. 
773 0 |d 2014  |g v. 2  |h pp. 834-845  |k n. 7  |p J. Mater. Chem. B  |x 20507518  |t Journal of Materials Chemistry B 
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856 4 0 |u https://doi.org/10.1039/c3tb21556c  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_20507518_v2_n7_p834_Gravina  |y Handle 
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