In vitro anti-Junin virus activity of a peptide isolated from Melia azedarach L. leaves
Meliacine, a peptide isolated from leaves of Melia azedarach L. inhibited the multiplication of Junin virus in Vero cells treated with the compound before infection (pre-treatment) or immediately after virus adsorption. Analysis of early events following infection demonstrated that meliacine blocks...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1998
|
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 10315caa a22012017a 4500 | ||
|---|---|---|---|
| 001 | PAPER-2968 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203226.0 | ||
| 008 | 190411s1998 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0032053094 | |
| 024 | 7 | |2 cas |a Antiviral Agents; Peptides, Cyclic; Plant Extracts | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a IAAGE | ||
| 100 | 1 | |a Castilla, V. | |
| 245 | 1 | 3 | |a In vitro anti-Junin virus activity of a peptide isolated from Melia azedarach L. leaves |
| 260 | |c 1998 | ||
| 270 | 1 | 0 | |m Castilla, V.; Laboratorio de Virologia, Departamento de Quimica Biologica, Facultad Ciencias Exactas Naturales, Pabellon 2, 1428 Buenos Aires, Argentina; email: viviana@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Weissenbacher, M.C., Laguens, R.P., Coto, C.E., Argentine hemorrhagic fever (1987) Curr Top Microbiol Immunol, 134, pp. 79-116 | ||
| 504 | |a Salas, R., De Manzione, N.M.C., Tesh, R.B., Venezuelan haemorrhagic fever (1991) Lancet, 338, pp. 1033-1036 | ||
| 504 | |a Coimbra, T.L.M., Nassar, E.S., Burattini, M.N., New arenavirus isolated in Brazil (1994) Lancet, 343, pp. 391-392 | ||
| 504 | |a Enría, D.A., Maiztegui, J.I., Antiviral treatment of Argentine hemorrhagic fever (1994) Antiviral Res, 23, pp. 23-31 | ||
| 504 | |a Leon, M.E., Coto, C.E., Inhibición de la multiplicación de los arenavirus Tacaribe, Pichinde y Junín en presencia de glucosamina o 2-deoxy-D-glucosa (1980) Rev Arg Microbiol, 12, pp. 59-61 | ||
| 504 | |a Daelli, M., Coto, C.E., Inhibición de la producción de partículas infecciosas en células infectadas con virus Junín en presencia de tunicamicina (1982) Rev Arg Microbiol, 14, pp. 171-176 | ||
| 504 | |a Damonte, E.B., Mersich, S.E., Candurra, N.A., Intracellular processing and transport of Junin virus glycoproteins influences virion infectivity (1994) Virus Res, 34, pp. 317-326 | ||
| 504 | |a Candurra, N.A., Maskin, L., Damonte, E.B., Inhibition of arenavirus multiplication in vitro by phenotiazines (1996) Antiviral Res, 31, pp. 149-158 | ||
| 504 | |a Weissenbacher, M.C., Avila, M.M., Calello, M.A., Merani, M.S., McCormick, J.B., Rodriguez, M., Effect of ribavirin and immune serum on Junin virus-infected primates (1986) Med Microbiol Immunol, 175, pp. 183-186 | ||
| 504 | |a McKee, K.T., Huggins, J.W., Trahan, C.J., Mahlandt, B.G., Rivabirin prophylaxis and therapy for experimental Argentine Hemorrhagic Fever (1988) Antimicrob Agents Chemother, 32, pp. 1304-1309 | ||
| 504 | |a Andrei, G.M., Lampuri, J.S., Coto, C.E., De Torres, R.A., An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice (1986) Experientia, 42, pp. 843-845 | ||
| 504 | |a Waschsman, M.B., Damonte, E.B., Coto, C.E., De Torres, R.A., Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells (1987) Antiviral Res, 8, pp. 1-12 | ||
| 504 | |a Villamil, S.M., Alché, L.E., Coto, C.E., Inhibition of herpes simplex virus type-1 multiplication by meliacine, a peptide of plant origin (1995) Antiviral Chem Chemother, 6, pp. 239-244 | ||
| 504 | |a Barquero, A., Alché, L.E., Coto, C.E., Antiviral activity of meliacine on the replication of a thymidine kinase-deficient (TK) mutant of herpes simplex virus type 1 alone and in combination with acyclovir (1997) Int J Antimicrob Agents, 9, pp. 49-55 | ||
| 504 | |a Wachsman, M.B., Castilla, V., Coto, C.E., Inhibition of foot and mouth disease virus (FMDV) uncoating by a plant-derived peptide isolated from Melia azedarach L. leaves (1998) Arch Virol, , (in press) | ||
| 504 | |a Andrei, G., Couto, A.S., De Lederkremer, R.M., Coto, C.E., Purification and partial characterization of an antiviral active peptide from Melia azedarach L. (1994) Antiviral Chem Chemother, 5, pp. 105-110 | ||
| 504 | |a Coulombié, F.C., Andrei, G.M., Laguens, R.P., De Torres, R.A., Coto, C.E., Partially purified leaf extracts of Melia azedarach L. inhibit Tacaribe virus growth in neonatal mice (1992) Phytother Res, 6, pp. 15-19 | ||
| 504 | |a Candurra, N.A., Damonte, E.B., Coto, C.E., Antigenic relationships among attenuated and pathogenic strains of Junin virus (1989) J Med Virol, 27, pp. 145-150 | ||
| 504 | |a Castilla, V., Mersich, S.E., Candurra, N.A., Damonte, E.B., The entry of Junin virus into Vero cells (1994) Arch Virol, 136, pp. 363-374 | ||
| 504 | |a Castilla, V., Mersich, S.E., Low-pH-induced fusion of Vero cells infected with Junin virus (1996) Arch Virol, 141, pp. 1307-1317 | ||
| 504 | |a Candurra, N.A., Scolaro, L.A., Mersich, S.E., Damonte, E.B., Coto, C.E., A comparison of Junin virus strains: Growth characteristics, cytopathogenicity and viral polypeptides (1990) Res Virol, 141, pp. 505-515 | ||
| 504 | |a Sanchez, A., Pifat, D.Y., Kenyon, R.H., Peters, C.J., Mc Cormick, J.B., Hiley, M.P., Junin virus monoclonal antiodies: Characterization and cross-reactivity with other arenaviruses (1989) J Gen Virol, 70, pp. 1125-1132 | ||
| 504 | |a Andrei, G.M., Damonte, E.B., De Torres, R.A., Coto, C.E., Induction of a cell refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L. (1988) Antiviral Res, 9, pp. 221-231 | ||
| 504 | |a Marsh, M., Helenius, A., Virus entry into animal cells (1989) Adv Virus Res, 36, pp. 107-151 | ||
| 504 | |a White, J.M., Viral and cellular membrane fusion proteins (1990) Annu Rev Physiol, 52, pp. 675-697 | ||
| 504 | |a Jones, J.S., Risser, R., Cell fusion induced by the murine leukemia virus envelope glycoprotein (1993) J Virol, 67, pp. 67-74 | ||
| 504 | |a Andersen, K.B., A domain of murine retrovirus surface protein gp70 mediates cell fusion, as shown in a novel SC-1 cell fusion system (1994) J Virol, 68, pp. 3175-3182 | ||
| 504 | |a Andrei, G.M., Coulombie, F.C., Courreges, M.C., De Torres, R.A., Coto, C.E., Meliacine, an antiviral compound from Melia azedarach L., inhibits interferon production (1990) J Interferon Res, 10, pp. 469-475 | ||
| 504 | |a Gresser, L., Morel-Maroger, L., Verroust, P., Riviere, Y., Gullon, J., Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocitic choriomeningitis virus (1978) Proc Natl Acad Sci USA, 75, pp. 1413-1416 | ||
| 504 | |a Levis, S.C., Saavedra, M.C., Ceccoli, C., Correlation between endogenous interferon and the clinical evolution of patients with Argentine hemorrhagic fever (1985) J Interferon Res, 5, pp. 383-389 | ||
| 520 | 3 | |a Meliacine, a peptide isolated from leaves of Melia azedarach L. inhibited the multiplication of Junin virus in Vero cells treated with the compound before infection (pre-treatment) or immediately after virus adsorption. Analysis of early events following infection demonstrated that meliacine blocks virus penetration by preventing the uncoating step. The addition of meliacine at different times after infection indicated that meliacine also interferes with the release of infectious particles to the extracellular medium and inhibits the low-pH-induced fusion of infected cells. Intracellular transport of viral glycoproteins to the cell membrane was not affected by meliacine, as revealed by immunofluorescence staining. Taken together, these results suggest that meliacine affects two events of the virus replicative cycle that require membrane fusion: uncoating and budding. |l eng | |
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: We are grateful to Isabel Paz for technical assistance and Dr A. Sanchez for his generous gift of monoclonal antibodies. This work was supported by grants from the Consejo Nacional de Investigaciones Cientificas y Técnicas (CONICET) and Universidad de Buones Aires. Dr C.E. Coto is a member of the Research Career from CONICET. | ||
| 593 | |a Depto. de Quim. Biológica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ANTIVIRAL PEPTIDE |
| 690 | 1 | 0 | |a ARENAVIRUSES |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a MELIACINE |
| 690 | 1 | 0 | |a MEMBRANE FUSION |
| 690 | 1 | 0 | |a ANTIVIRUS AGENT |
| 690 | 1 | 0 | |a MELIACINE |
| 690 | 1 | 0 | |a PLANT EXTRACT |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a VIRUS GLYCOPROTEIN |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a ANTIVIRAL ACTIVITY |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CELL FUSION |
| 690 | 1 | 0 | |a CONCENTRATION RESPONSE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a IN VITRO STUDY |
| 690 | 1 | 0 | |a INTRACELLULAR TRANSPORT |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PLANT LEAF |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a VERO CELL |
| 690 | 1 | 0 | |a VIRUS ADSORPTION |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a ANTIVIRAL AGENTS |
| 690 | 1 | 0 | |a CERCOPITHECUS AETHIOPS |
| 690 | 1 | 0 | |a DOSE-RESPONSE RELATIONSHIP, DRUG |
| 690 | 1 | 0 | |a FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT |
| 690 | 1 | 0 | |a GIANT CELLS |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a MEMBRANE FUSION |
| 690 | 1 | 0 | |a PEPTIDES, CYCLIC |
| 690 | 1 | 0 | |a PLANT EXTRACTS |
| 690 | 1 | 0 | |a PLANT LEAVES |
| 690 | 1 | 0 | |a TIME FACTORS |
| 690 | 1 | 0 | |a VERO CELLS |
| 700 | 1 | |a Barquero, A.A. | |
| 700 | 1 | |a Mersich, S.E. | |
| 700 | 1 | |a Coto, C.E. | |
| 773 | 0 | |d 1998 |g v. 10 |h pp. 67-75 |k n. 1 |p Int. J. Antimicrob. Agents |x 09248579 |w (AR-BaUEN)CENRE-5213 |t International Journal of Antimicrobial Agents | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032053094&doi=10.1016%2fS0924-8579%2898%2900011-9&partnerID=40&md5=1844b414f99b3c35d96deb4be9d7433f |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/S0924-8579(98)00011-9 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_09248579_v10_n1_p67_Castilla |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09248579_v10_n1_p67_Castilla |y Registro en la Biblioteca Digital |
| 961 | |a paper_09248579_v10_n1_p67_Castilla |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 63921 | ||