Seasonal changes in the activity of 11β-hydroxysteroid dehydrogenase in toad testes
In mammals, glucocorticoids (GC) are inactivated by the oxidative activity of 11β-hydroxysteroid dehydrogenase (11β-HSD). To study that mechanism in the testes of Bufo arenarum, 11β-HSD activity and plasma corticosterone (B) were determined in toads from pre- (PR), post- (P), and reproductive (R) pe...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
New York Academy of Sciences
2005
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 04667caa a22008297a 4500 | ||
|---|---|---|---|
| 001 | PAPER-4029 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203332.0 | ||
| 008 | 190411s2005 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-22144449573 | |
| 024 | 7 | |2 cas |a 11beta hydroxysteroid dehydrogenase, 9041-46-7; corticosterone, 50-22-6; glucose 6 phosphatase, 9001-39-2; glycyrrhetinic acid, 471-53-4; nicotinamide adenine dinucleotide, 53-84-9; succinate dehydrogenase, 9002-02-2, 9028-10-8 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a ANYAA | ||
| 100 | 1 | |a Denari, D. | |
| 245 | 1 | 0 | |a Seasonal changes in the activity of 11β-hydroxysteroid dehydrogenase in toad testes |
| 260 | |b New York Academy of Sciences |c 2005 | ||
| 270 | 1 | 0 | |m Ceballos, N.R.; Departamento de Biodiversidad y Biologia Experimental, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina; email: nceballo@bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Funder, J.W., (1997) Annu. Rev. Med., 48, pp. 231-240 | ||
| 504 | |a White, P.C., Mune, T., Agarwal, A.K., (1997) Endocr. Rev., 18, pp. 135-156 | ||
| 504 | |a Brem, A., Matheson, K., Latif, S., Morris, D., (1993) Am. J. Physiol., 264, pp. F854-F858 | ||
| 504 | |a Monder, C., Sakai, R.R., Miroff, Y., (1994) Endocrinology, 134, pp. 1193-1198 | ||
| 504 | |a Gao, H.-B., Ge, R.-S., Lakshmi, V., (1997) Endocrinology, 138, pp. 156-161 | ||
| 504 | |a Romero, L.M., (2002) Gen. Comp. Endocrinol., 128, pp. 1-24 | ||
| 504 | |a Pozzi, A., Lantos, C., Ceballos, N., (1997) Gen. Comp. Endocrinol., 106, pp. 400-406 | ||
| 520 | 3 | |a In mammals, glucocorticoids (GC) are inactivated by the oxidative activity of 11β-hydroxysteroid dehydrogenase (11β-HSD). To study that mechanism in the testes of Bufo arenarum, 11β-HSD activity and plasma corticosterone (B) were determined in toads from pre- (PR), post- (P), and reproductive (R) periods. Toad 11β-HSD is NAD+-dependent and strongly inhibited by glycyrrhetinic acid. Vmax is higher in the P period (1.37 vs. R: 0.13 and PR: 0.26 pmol/min-mg protein), whereas Km values (around 200 nM) remain constant. Plasma B concentrations (R: 178; PR: 61; P: 114 nM) are close to Km values, suggesting that, under baseline conditions, 11β-HSD could protect testes against GC action. © 2005 New York Academy of Sciences. |l eng | |
| 593 | |a Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 593 | |a Departamento de Biodiversidad y Biologia Experimental, Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, C1428EHA Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a 11Β-HYDROXYSTEROID DEHYDROGENASE |
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a TESTIS |
| 690 | 1 | 0 | |a TOAD |
| 690 | 1 | 0 | |a 11BETA HYDROXYSTEROID DEHYDROGENASE |
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a GLUCOCORTICOID |
| 690 | 1 | 0 | |a GLUCOSE 6 PHOSPHATASE |
| 690 | 1 | 0 | |a GLYCYRRHETINIC ACID |
| 690 | 1 | 0 | |a NICOTINAMIDE ADENINE DINUCLEOTIDE |
| 690 | 1 | 0 | |a SUCCINATE DEHYDROGENASE |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a CELL NUCLEUS |
| 690 | 1 | 0 | |a CELLULAR DISTRIBUTION |
| 690 | 1 | 0 | |a CONFERENCE PAPER |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CORTICOSTERONE BLOOD LEVEL |
| 690 | 1 | 0 | |a CYTOSOL |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a LEYDIG CELL |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MICHAELIS CONSTANT |
| 690 | 1 | 0 | |a MICROSOME |
| 690 | 1 | 0 | |a MITOCHONDRION |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a OXIDATION |
| 690 | 1 | 0 | |a REPRODUCTION |
| 690 | 1 | 0 | |a SEASONAL VARIATION |
| 690 | 1 | 0 | |a TESTIS |
| 690 | 1 | 0 | |a TOAD |
| 690 | 1 | 0 | |a ANURA |
| 690 | 1 | 0 | |a BUFO ARENARUM |
| 690 | 1 | 0 | |a MAMMALIA |
| 700 | 1 | |a Ceballos, N.R. | |
| 773 | 0 | |d New York Academy of Sciences, 2005 |g v. 1040 |h pp. 297-300 |p Ann. New York Acad. Sci. |x 00778923 |w (AR-BaUEN)CENRE-1541 |t Annals of the New York Academy of Sciences | |
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| 856 | 4 | 0 | |u https://doi.org/10.1196/annals.1327.046 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00778923_v1040_n_p297_Denari |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00778923_v1040_n_p297_Denari |y Registro en la Biblioteca Digital |
| 961 | |a paper_00778923_v1040_n_p297_Denari |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 64982 | ||