Convenient syntheses of 5-O- and 3,5-di-O-(β-d-galactofuranosyl)-d-galactofuranose

Benzoylation of d-galactono-1,4-lactone with 2.2 mol of benzoyl chloride, at -23°, gave the 2,6-dibenzoate (2, 62%). Tin(IV) chloride-catalyzed glycosylation of 2 with 1,2,3,5,6-penta-O-benzoyl-α,β-d-galactofuranose (1) afforded 2,6-di-O-benzoyl-5-O-(2,3,5,6-tetra-O-benzoyl-β-d-galactofuranosyl)-d-g...

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Autor principal: de Lederkremer, R.M
Otros Autores: Marino, C., Varela, O.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1990
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-0025714097 
024 7 |2 cas  |a 3,5-di-O-(beta-galactofuranosyl)-galactofuranose, 129728-10-5; 5-O-beta-galactofuranosyl-galactofuranose, 129728-07-0; Disaccharides; Trisaccharides 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a CRBRA 
100 1 |a de Lederkremer, R.M. 
245 1 0 |a Convenient syntheses of 5-O- and 3,5-di-O-(β-d-galactofuranosyl)-d-galactofuranose 
260 |c 1990 
270 1 0 |m de Lederkremer, R.M.; Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellon II, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a McNeill, Wallner, Hunter, Brennan, (1987) Carbohydr. Res., 166, pp. 299-308 
504 |a Notermans, Veeneman, van Zuylen, Hoogerhout, van Boom, (1988) Mol. Immunol., 25, pp. 975-979 
504 |a Bennett, Bhattacharjee, Glaudemans, (1985) Mol. Immun., 22, pp. 251-254 
504 |a Mendonça-Previato, Gorin, Travassos, (1980) Infect. Immun., 29, pp. 934-939 
504 |a Gander, Jentoft, Drewes, Rick, (1974) J. Biol. Chem., 249, pp. 2063-2072 
504 |a Schnaidman, Yoshida, Gorin, Travassos, (1986) J. Protozool., 33, pp. 186-191 
504 |a de Lederkremer, Casal, Alves, Colli, (1980) FEBS Lett., 116, pp. 25-29 
504 |a du Mortier, Varela, de Lederkremer, (1989) Carbohydr. Res., 189, pp. 79-86 
504 |a Marino, Varela, de Lederkremer, (1989) Carbohydr. Res., 190, pp. 65-76 
504 |a Gorin, Spencer, 5-O-β-D-GALACTOFURANOSYL-D-GALACTOSE FROM GALACTOCARALOSE (1959) Canadian Journal of Chemistry, 37, pp. 499-502 
504 |a Fernandez Cirelli, Sznaidman, Varela, de Lederkremer, (1983) Tetrahedron, 39, pp. 313-316 
504 |a Bock, Pedersen, (1983) Adv. Carbohydr. Chem. Biochem., 41, pp. 27-66 
504 |a D'Accorso, Thiel, Schüller, (1983) Carbohydr. Res., 124, pp. 177-184 
504 |a Hanessian, Banoub, (1977) Carbohydr. Res., 59, pp. 261-267 
504 |a Bundle, Lemieux, (1976) Methods Carbohydr. Chem., 7, pp. 79-86 
504 |a Lerner, (1972) Methods Carbohydr. Chem., 6, pp. 131-134 
504 |a van Heeswijk, Visser, Vliegenthart, (1977) Carbohydr. Res., 59, pp. 81-86 
504 |a Sugawara, Nakayama, Ogawa, Synthetic studies on glycosidic phytotoxins. Part III. Synthetic studies on derivatives of 5-O-.BETA.-D-galactofuranosyl-D-galactofuranose. (1986) Agricultural and Biological Chemistry, 50, pp. 1557-1561 
520 3 |a Benzoylation of d-galactono-1,4-lactone with 2.2 mol of benzoyl chloride, at -23°, gave the 2,6-dibenzoate (2, 62%). Tin(IV) chloride-catalyzed glycosylation of 2 with 1,2,3,5,6-penta-O-benzoyl-α,β-d-galactofuranose (1) afforded 2,6-di-O-benzoyl-5-O-(2,3,5,6-tetra-O-benzoyl-β-d-galactofuranosyl)-d-galactono-1,4-lactone (4, 70%), HO-3 of which was benzoylated to give 5. The structure of 4 was confirmed by its conversion into crystalline β-d-Galf-(1→5)-d-Gal-ol (8). Reduction of the lactone function of 5 with di-isoamylborane followed by debenzoylation gave β-d-Galf-(1→5)-d-Galf (7). A by-product of the condensation of 1 with 2 was characterized as 2,6-di-O-benzoyl-3,5-di-O-(2,3,5,6-tetra-O-benzoyl-β-d-galactofuranosyl)-d-galactono-1,4-lactone (9), which was converted, as for 5, into β-d-Galf-(1→3)[β-d-Galf-(1→5)]-d-Galf (13). © 1990.  |l eng 
536 |a Detalles de la financiación: Universidad de Buenos Aires 
536 |a Detalles de la financiación: We thank CONICET (Consejo National de Investigaciones Cientificas y TCc-nicas), the University of Buenos Aires, and UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases for financial support. and UMYMFOR (CONICET-KEN, Buenos Aires) for the microanalyses. 
593 |a Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellon II, 1428 Buenos Aires, Argentina 
690 1 0 |a 3,5 DI O (BETA GALACTOFURANOSYL) GALACTOFURANOSE 
690 1 0 |a 3,5-DI-O-(BETA-GALACTOFURANOSYL)-GALACTOFURANOSE 
690 1 0 |a 5 O BETA GALACTOFURANOSYL GALACTOFURANOSE 
690 1 0 |a 5-O-BETA-GALACTOFURANOSYL-GALACTOFURANOSE 
690 1 0 |a DISACCHARIDE 
690 1 0 |a TRISACCHARIDE 
690 1 0 |a ARTICLE 
690 1 0 |a CARBOHYDRATE ANALYSIS 
690 1 0 |a CHEMISTRY 
690 1 0 |a MOLECULAR GENETICS 
690 1 0 |a SYNTHESIS 
690 1 0 |a CARBOHYDRATE SEQUENCE 
690 1 0 |a CHEMISTRY 
690 1 0 |a DISACCHARIDES 
690 1 0 |a MOLECULAR SEQUENCE DATA 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a TRISACCHARIDES 
700 1 |a Marino, C. 
700 1 |a Varela, O. 
773 0 |d 1990  |g v. 200  |h pp. 227-235  |k n. C  |p Carbohydr. Res.  |x 00086215  |w (AR-BaUEN)CENRE-301  |t Carbohydrate Research 
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856 4 0 |u https://doi.org/10.1016/0008-6215(90)84193-X  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_00086215_v200_nC_p227_deLederkremer  |y Handle 
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