Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy
As part of the development of an analytical technique for the detection of meridianins and related compounds in biological fluids, a crude extract of the tunicate Aplidium meridianum was analysed using neutral loss tandem mass spectrometry. The 41 u neutral loss-EI(+) mass spectrum showed molecular...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
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2007
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 06038caa a22008777a 4500 | ||
|---|---|---|---|
| 001 | PAPER-6596 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203617.0 | ||
| 008 | 190411s2007 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-34548577508 | |
| 024 | 7 | |2 cas |a Alkaloids; Indole Alkaloids; meridianin F; meridianin G | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a NPRAA | ||
| 100 | 1 | |a Seldes, A.M. | |
| 245 | 1 | 0 | |a Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy |
| 260 | |c 2007 | ||
| 270 | 1 | 0 | |m Palermo, J.A.; Facultad de Ciencias Exactas y Naturales, Departamento de Quimica Organica, Universidad de Buenos Aires, Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Franco, L., Hernandez Joffe, E., Bal de Kier Puricelli, L., Tatian, M., Seldes, A.M., Palermo, J.A., (1998) J. Nat. Prod., 61, p. 1130 | ||
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| 504 | |a Fresneda, P.M., Molina, P., Bleda, J.A., (2001) Tetrahedron, 57, p. 200157 | ||
| 504 | |a Stefanowicz, P., Prasain, J.K., Yeboah, K.F., Konishi, Y., (2001) Anal. Chem., 73, p. 3583 | ||
| 504 | |a Fang, S., Hao, C., Sun, W., Liu, Z., Liu, S., (1999) Planta Medica, 65, p. 68 | ||
| 504 | |a Fang, S., Hao, C., Sun, W., Liu, Z., Liu, S., (1998) Rapid Comm. Mass Spectr., 12, p. 589 | ||
| 504 | |a Brombacher, S., Edmonds, S., Volmer, D.A., (2002) Rapid Comm. Mass Spectr., 16, p. 2306 | ||
| 504 | |a Pergantis, S.A., Wangkam, S., Francesconi, K.A., Thomas-Oates, J.E., (2000) Anal. Chem., 72, p. 357 | ||
| 504 | |a Hsu, F., Turk, J., (2004) J. Am. Soc. Mass Spectr., 15, p. 1 | ||
| 504 | |a Prasain, J.K., Ueki, M., Stefanowicz, P., Osada, H., (2002) J. Mass Spectr., 37, p. 283 | ||
| 520 | 3 | |a As part of the development of an analytical technique for the detection of meridianins and related compounds in biological fluids, a crude extract of the tunicate Aplidium meridianum was analysed using neutral loss tandem mass spectrometry. The 41 u neutral loss-EI(+) mass spectrum showed molecular ions corresponding to two previously undetected alkaloids. We report herein the isolation and structure elucidation of these alkaloids, meridianins F and G. |l eng | |
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires, X-122, PICT 98-06-03614 | ||
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: We thank Lic. Enrique Marschoff (Instituto Antártico Argentino), Dr Daniel Nahabedian and Dr Javier Calcagno (Departamento de Ciencias Biológicas, FCEN, Universidad de Buenos Aires) for sample collection, and the scientific team and crew of the BIP Dr Holmberg for their collaboration. We are indebted to Drs Elisa Bal de Kier Joffé and Lydia Puricelli (Instituto de Oncología ‘‘Angel Roffo’’, Buenos Aires) for the bioassays, and the technical assistance of Mrs Alicia Rivelli is greatly appreciated. We are also indebted to LANAIS–EMAR (CONICET–FCEN, UBA) for mass spectra and UMYMFOR (CONICET–FCEN, UBA) for NMR spectra. We thank Dr Michael Grayson (Center for Biomedical and Bioorganic Mass Spectrometry, Washington University, St Louis, Mo. USA) for additional tandem mass spectrometry experiments. L.H.F. acknowledges a research fellowship from CONICET. M.F.R.B. acknowledges a research fellowship from ANPCyT. This research was partially supported by grants from Universidad de Buenos Aires (grant X-122), CONICET and ANPCyT (PICT 98-06-03614). | ||
| 593 | |a Facultad de Ciencias Exactas y Naturales, Departamento de Quimica Organica, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CONSTANT NEUTRAL LOSS |
| 690 | 1 | 0 | |a INDOLE ALKALOIDS |
| 690 | 1 | 0 | |a MARINE NATURAL PRODUCTS |
| 690 | 1 | 0 | |a MERIDIANINS |
| 690 | 1 | 0 | |a TANDEM MASS SPECTROMETRY |
| 690 | 1 | 0 | |a ALKALOID DERIVATIVE |
| 690 | 1 | 0 | |a MERIDIANIN F |
| 690 | 1 | 0 | |a MERIDIANIN G |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DRUG IDENTIFICATION |
| 690 | 1 | 0 | |a DRUG ISOLATION |
| 690 | 1 | 0 | |a DRUG STRUCTURE |
| 690 | 1 | 0 | |a ELECTROSPRAY MASS SPECTROMETRY |
| 690 | 1 | 0 | |a INFRARED SPECTROPHOTOMETRY |
| 690 | 1 | 0 | |a MARINE SPECIES |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PROTON NUCLEAR MAGNETIC RESONANCE |
| 690 | 1 | 0 | |a TANDEM MASS SPECTROMETRY |
| 690 | 1 | 0 | |a ULTRAVIOLET SPECTROPHOTOMETRY |
| 690 | 1 | 0 | |a ALKALOIDS |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a INDOLE ALKALOIDS |
| 690 | 1 | 0 | |a MOLECULAR STRUCTURE |
| 690 | 1 | 0 | |a TANDEM MASS SPECTROMETRY |
| 690 | 1 | 0 | |a UROCHORDATA |
| 690 | 1 | 0 | |a APLIDIUM MERIDIANUM |
| 700 | 1 | |a Brasco, M.F.R. | |
| 700 | 1 | |a Franco, L.H. | |
| 700 | 1 | |a Palermo, J.A. | |
| 773 | 0 | |d 2007 |g v. 21 |h pp. 555-563 |k n. 6 |p Nat. Prod. Res. |x 14786419 |t Natural Product Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548577508&doi=10.1080%2f14786410601133517&partnerID=40&md5=4451e8f6611899cb65990309da1f293a |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1080/14786410601133517 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_14786419_v21_n6_p555_Seldes |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14786419_v21_n6_p555_Seldes |y Registro en la Biblioteca Digital |
| 961 | |a paper_14786419_v21_n6_p555_Seldes |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 67549 | ||