Validation and development of a clinical prediction rule in clinically suspected community-acquired pneumonia
Objectives: To develop a mathematical model to predict the probability of having community-acquired pneumonia and to evaluate an already developed prediction rule that has not been validated in a clinical scenario. Methods: Children who presented with fever and had presumptive clinical diagnosis of...
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| Otros Autores: | , , , , , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2010
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 13112caa a22019217a 4500 | ||
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| 001 | PAPER-7843 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203737.0 | ||
| 008 | 190411s2010 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-77953356166 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a PECAE | ||
| 100 | 1 | |a Bilkis, M.D. | |
| 245 | 1 | 0 | |a Validation and development of a clinical prediction rule in clinically suspected community-acquired pneumonia |
| 260 | |c 2010 | ||
| 270 | 1 | 0 | |m Bilkis, M. D., Cesar Díaz 2071 (C. P. 1416), Capital Federal, Argentina; email: mbilkis@gmail.com |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a McIntosh, K., Community-acquired pneumonia in children (2002) N Engl J Med, 346 (6), pp. 429-437 | ||
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| 504 | |a Halm, E.A., Teirstein, A.S., Management of community acquired pneumonia (2002) N Engl J Med, 347 (25), pp. 2039-2045 | ||
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| 504 | |a Moreno, L., Krishnan, J., Durán, P., Development and validation of a clinical prediction rule to distinguish bacterial from viral pneumonia in children (2006) Pediatr Pulmonol, 41, pp. 331-337 | ||
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| 504 | |a Marcus, N., Mor, M., Mimouni, M., Validity of the quick-read CRP in the prediction of bacterial pneumonia and gastroenteritis in the pediatric emergencies department (2005) Eur J Med Emerg, 12 (4), p. 208 | ||
| 504 | |a Mullholand, E., Simoes, E., Costales, M., Standardized diagnosis of pneumonia in developing countries (1992) Pediatr Infect Dis J, 11 (2), pp. 77-81 | ||
| 504 | |a Sachdev, H., Mahajan, S., Garg, A., Improving antibiotic and bronchodilator prescription in children presenting with difficult breathing: Experience from an urban hospital in India (2001) Indian Pediatr, 38, pp. 827-838 | ||
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| 504 | |a Simon, H., Khan, N., Nordenberg, D., Pediatric emergency physician interpretation of plan radiographs: Is routine review by a radiologist necessary and cost effective? (1996) Ann Emerg Med, 27 (3), pp. 295-298 | ||
| 504 | |a Risgby, C., Strife, J., Johnson, N., Is the frontal radiograph alone sufficient to evaluate for pneumonia in children? (2004) Pediatr Radiol, 34, pp. 379-383 | ||
| 504 | |a Lynch, T., Gouin, S., Larson, C., Does the lateral chest radiograph help pediatric emergency physicians diagnose pneumonia? A randomized clinical trial (2004) Acad Emerg Med, 11 (6), pp. 625-629 | ||
| 504 | |a Dyke, T., Brown, N., Hypoxia in childhood pneumonia: Better detection and more oxygen needed in developing countries (1994) BMJ, 308, pp. 119-120 | ||
| 504 | |a Tanen, A., Trocinski, D., The use of pulse oximetry to exclude pneumonia in children (2002) Am J Emerg Med, 20, pp. 521-523 | ||
| 504 | |a Margolis, P., Gadomski, A., Does this infant have pneumonia? (1998) JAMA, 279 (4), pp. 308-313 | ||
| 504 | |a Mahabee-Gittens, M., Bachman, D., Shapiro, E., Chest radiographs in the pediatric emergency department for children e18 months of age with wheezing (1999) Clin Pediatr, 38, pp. 395-399 | ||
| 504 | |a Nascimento-Carvalho, C., Rocha, H., Santos-Jesus, R., Childhood pneumonia: Clinical aspects associated with hospitalization or death (2002) BJID, 6 (1), pp. 22-28 | ||
| 504 | |a Rothrock, S., Green, S., Fanelli, J., Do published guidelines predict pneumonia in children presenting to an urban ED? (2001) Pediatr Emerg Care, 17 (4), pp. 240-243 | ||
| 504 | |a Mahabee-Gittens, M., Grupp-Phelan, J., Brody, A., Identifying children with pneumonia in the emergency department (2005) Clin Pediatr, 44, pp. 427-435 | ||
| 504 | |a Turner, R., Lande, A., Chase, P., Pneumonia in pediatric outpatients: Cause and clinical manifestations (1987) J Pediatr, 111, pp. 194-200 | ||
| 504 | |a Nascimento-Carvalho, C., Lopes, A., Gomes, M., Community acquired pneumonia among pediatric outpatients in Salvador, Northeast Brazil, with emphasis on the role of pneumococcus (2001) BJID, 5 (1), pp. 13-20 | ||
| 504 | |a Lynch, T., Platt, R., Gouin, S., Can we predict which children with clinically suspected pneumonia will have the presence of focal infiltrates on chest radiographs? (2004) Pediatrics, 113, pp. e186-e189 | ||
| 504 | |a Pineda Solas, V., Aspectos clinicoepidemiológicos de la neumonía neumocócica. Diagnó stico diferencial (2003) An Pediatr, 1 (2), pp. 14-17 | ||
| 504 | |a Swischuk, L., Transfer for Bpneumonia (2003) Pediatr Emerg Care, 19 (3), pp. 203-205 | ||
| 504 | |a Hazir, T., Bin Nisar, Y., Qazi, S., Chest radiography in children aged 2-59 months diagnosed with non-severe pneumonia as defined by World Health Organization: Descriptive multicentre study in Pakistan (2006) BMJ, 333 (7569), pp. 629-633 | ||
| 504 | |a Buňuel, Á., Lvarez, J.C., Vila Pablos, C., Heredia Quiciós, C., Utilidad de la exploración f?́sica para el diagnó stico de neumonía infantil adquirida en la comunidad en un centro de atención primaria (2003) Aten Primaria, 32 (6), pp. 349-354 | ||
| 504 | |a Ayieko, P., English, M., Case management of childhood pneumonia in developing countries (2007) Pediatr Infect Dis J, 26, pp. 432-440 | ||
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| 504 | |a Cherian, T., Mulholland, E.K., Carlin, J.B., Standardized interpretation of pediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies (2005) Bull WHO, 83, pp. 353-359 | ||
| 504 | |a Jcr, P., Tonelli, P., Barros, L.C., Clinical signs of pneumonia in children: Association with and prediction of diagnosis by fuzzy sets theory (2004) Braz J Med Biol Res, 37 (5), pp. 701-709 | ||
| 520 | 3 | |a Objectives: To develop a mathematical model to predict the probability of having community-acquired pneumonia and to evaluate an already developed prediction rule that has not been validated in a clinical scenario. Methods: Children who presented with fever and had presumptive clinical diagnosis of pneumonia were evaluated in 4 institutions of different complexity during 1 year. The variables assessed were sex, age, respiratory rate, days with fever, maximum body temperature, presence of tachypnea, cough, chest pain, intercostal retraction, nasal flaring, abdominal pain, vomiting, grunting, rales, decreased breath sounds, wheezing, fatigue, loss of appetite, loss of sleep, and season of the year. The chest radiographs were photographed and then interpreted by 2 pediatric radiologists. Results: A total of 257 children were evaluated: 179 (69%) had clinical and radiological diagnosis of community-acquired pneumonia, and 78 (30%) had no radiological confirmation. A total of 96 photographs were recorded, and in 64 of the cases, there was agreement in the diagnosis between the evaluating pediatrician and the radiologists (κ index = 0.68).With the calculated probabilities, it was possible to build a receiving operating characteristic curve and, based on the estimated coefficients we calculated, a value associated to the probability of having pneumonia. Conclusions: We developed a model including 5 variables of high level of sensitivity for the diagnosis of pneumonia. To use it, it would be useful to apply the appropriate software. In addition, we validated a clinical prediction rule of 4 variables that proved to have 93.8% sensitivity to diagnose pneumonia in children with a fever and localized rales, or decreased breath sounds, or tachypnea, or any combination of these 4 variables. Copyright © 2010 by Lippincott Williams & Wilkins. |l eng | |
| 593 | |a Emergency Department, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina | ||
| 593 | |a Pediatric Emergency Department, Centro Hospitalario Pereira Rossell, Montevideo, Uruguay | ||
| 593 | |a Emergency Department, Hospital de Agudos Diego Paroissien, La Matanza, Spain | ||
| 593 | |a Policlínico Del Docente, Italy | ||
| 593 | |a Emergency Department, Hospital de Agudos Enrique Tornú, Italy | ||
| 593 | |a Department of Images, Hospital de Niños Ricardo Gutiérrez, Universidad de Buenos Aires, Argentina | ||
| 593 | |a Instituto de Cálculo, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 593 | |a Facultad de Medicina, Universidad de la República, Uruguay | ||
| 690 | 1 | 0 | |a CHEST RADIOGRAPHS |
| 690 | 1 | 0 | |a PREDICTIVE FACTORS |
| 690 | 1 | 0 | |a ABDOMINAL PAIN |
| 690 | 1 | 0 | |a ABNORMAL RESPIRATORY SOUND |
| 690 | 1 | 0 | |a ADOLESCENT |
| 690 | 1 | 0 | |a AGE DISTRIBUTION |
| 690 | 1 | 0 | |a ANOREXIA |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a BODY TEMPERATURE |
| 690 | 1 | 0 | |a BREATHING RATE |
| 690 | 1 | 0 | |a CHILD |
| 690 | 1 | 0 | |a COMMUNITY ACQUIRED PNEUMONIA |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CORRELATION COEFFICIENT |
| 690 | 1 | 0 | |a COUGHING |
| 690 | 1 | 0 | |a FALSE NEGATIVE RESULT |
| 690 | 1 | 0 | |a FALSE POSITIVE RESULT |
| 690 | 1 | 0 | |a FATIGUE |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a FEVER |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a INFANT |
| 690 | 1 | 0 | |a INTERCOSTAL RETRACTION |
| 690 | 1 | 0 | |a MAJOR CLINICAL STUDY |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MATHEMATICAL MODEL |
| 690 | 1 | 0 | |a NOSE CONGESTION |
| 690 | 1 | 0 | |a PEDIATRICIAN |
| 690 | 1 | 0 | |a PREDICTION |
| 690 | 1 | 0 | |a PROBABILITY |
| 690 | 1 | 0 | |a RECEIVER OPERATING CHARACTERISTIC |
| 690 | 1 | 0 | |a SENSITIVITY AND SPECIFICITY |
| 690 | 1 | 0 | |a SEX RATIO |
| 690 | 1 | 0 | |a SLEEP DISORDER |
| 690 | 1 | 0 | |a TACHYPNEA |
| 690 | 1 | 0 | |a THORAX DISEASE |
| 690 | 1 | 0 | |a THORAX PAIN |
| 690 | 1 | 0 | |a THORAX RADIOGRAPHY |
| 690 | 1 | 0 | |a VALIDATION PROCESS |
| 690 | 1 | 0 | |a WHEEZING |
| 690 | 1 | 0 | |a CLINICAL TRIAL |
| 690 | 1 | 0 | |a COMMUNITY-ACQUIRED INFECTIONS |
| 690 | 1 | 0 | |a DIFFERENTIAL DIAGNOSIS |
| 690 | 1 | 0 | |a MULTICENTER STUDY |
| 690 | 1 | 0 | |a PREDICTIVE VALUE |
| 690 | 1 | 0 | |a PRESCHOOL CHILD |
| 690 | 1 | 0 | |a RADIOGRAPHY |
| 690 | 1 | 0 | |a RISK FACTOR |
| 690 | 1 | 0 | |a STATISTICAL MODEL |
| 690 | 1 | 0 | |a VALIDATION STUDY |
| 690 | 1 | 0 | |a ADOLESCENT |
| 690 | 1 | 0 | |a CHILD |
| 690 | 1 | 0 | |a CHILD, PRESCHOOL |
| 690 | 1 | 0 | |a COMMUNITY-ACQUIRED INFECTIONS |
| 690 | 1 | 0 | |a DIAGNOSIS, DIFFERENTIAL |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a INFANT |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MODELS, STATISTICAL |
| 690 | 1 | 0 | |a PREDICTIVE VALUE OF TESTS |
| 690 | 1 | 0 | |a PROBABILITY |
| 690 | 1 | 0 | |a RADIOGRAPHY, THORACIC |
| 690 | 1 | 0 | |a RISK FACTORS |
| 690 | 1 | 0 | |a ROC CURVE |
| 690 | 1 | 0 | |a SENSITIVITY AND SPECIFICITY |
| 690 | 1 | 0 | |a ADOLESCENT |
| 690 | 1 | 0 | |a CHILD |
| 690 | 1 | 0 | |a CHILD, PRESCHOOL |
| 690 | 1 | 0 | |a COMMUNITY-ACQUIRED INFECTIONS |
| 690 | 1 | 0 | |a DIAGNOSIS, DIFFERENTIAL |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a INFANT |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MODELS, STATISTICAL |
| 690 | 1 | 0 | |a PREDICTIVE VALUE OF TESTS |
| 690 | 1 | 0 | |a PROBABILITY |
| 690 | 1 | 0 | |a RADIOGRAPHY, THORACIC |
| 690 | 1 | 0 | |a RISK FACTORS |
| 690 | 1 | 0 | |a ROC CURVE |
| 690 | 1 | 0 | |a SENSITIVITY AND SPECIFICITY |
| 650 | 1 | 7 | |2 spines |a PNEUMONIA |
| 650 | 1 | 7 | |2 spines |a PNEUMONIA |
| 650 | 1 | 7 | |2 spines |a PNEUMONIA |
| 650 | 1 | 7 | |2 spines |a PNEUMONIA |
| 650 | 1 | 7 | |2 spines |a PNEUMONIA |
| 700 | 1 | |a Gorgal, N. | |
| 700 | 1 | |a Carbone, M. | |
| 700 | 1 | |a Vazquez, M. | |
| 700 | 1 | |a Albanese, P. | |
| 700 | 1 | |a Branda, M.C. | |
| 700 | 1 | |a Alterman, E. | |
| 700 | 1 | |a Rodriguez, D. | |
| 700 | 1 | |a Orellana, L. | |
| 700 | 1 | |a Pedrosa, O.B. | |
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