Mast cell phenotypes and microvessels in non-small cell lung cancer and its prognostic significance
The impact of interstitial inflammatory cells, such as mast cells, and angiogenesis on the prognosis of cancer patients has been reported in many solid tumors, although there is disagreement about their role. We undertook a retrospective study with tissue samples from 65 patients with stage I and II...
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| Formato: | Capítulo de libro |
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2010
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 11280caa a22013457a 4500 | ||
|---|---|---|---|
| 001 | PAPER-7906 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203741.0 | ||
| 008 | 190411s2010 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-77950692149 | |
| 024 | 7 | |2 cas |a chymase, 75496-62-7, 97501-92-3; tryptase, 97501-93-4 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a HPCQA | ||
| 100 | 1 | |a Carlini, M.J. | |
| 245 | 1 | 0 | |a Mast cell phenotypes and microvessels in non-small cell lung cancer and its prognostic significance |
| 260 | |c 2010 | ||
| 270 | 1 | 0 | |m Lauría de Cidre, L.S.; Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires C1428EGA, Argentina; email: laurial@bg.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Matos, E.L., Loria, D.I., Zengarini, N., (2003) Atlas of cancer mortality in Argentina 1997-2001 (Spanish), , Fundación Bunge y Born, Buenos Aires (Argentina) | ||
| 504 | |a Mueller, M.M., Fusening, N.E., Friends or foes. Bipolar effects of the tumour stroma in cancer (2004) Nature, 4, pp. 839-849 | ||
| 504 | |a Ribatti, D., Ennas, M.G., Vacca, A., Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma (2003) Eur J Clin Invest, 33, pp. 420-425 | ||
| 504 | |a Mauro, L.V., Bellido, M., Morandi, A., Association between mast cells of different phenotypes and angiogenesis in colorectal cancer (2008) Mol Med Rep, 1, p. 8 | ||
| 504 | |a Kankkunen, J.P., Harvima, I.T., Naukkarinen, A., Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions (1997) Int J Cancer, 72, pp. 385-388 | ||
| 504 | |a Imada, A., Shijubo, N., Kojima, H., Abe, S., Mast cells correlate with angiogenesis and poor outcome in stage I lung adenocarcinoma (2000) Eur Respir J, 15, pp. 1087-1093 | ||
| 504 | |a Takanami, I., Takeuchi, K., Naruke, M., Mast cell density is associated with angiogenesis and poor prognosis in pulmonary adenocarcinoma (2000) Cancer, 88, pp. 2686-2692 | ||
| 504 | |a Hallgren, J., Pejler, G., Biology of mast cell tryptase. An inflammatory mediator (2006) FEBS J, 273, pp. 1871-1895 | ||
| 504 | |a Blair, R.J., Meng, H., Marchese, M.J., Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor (1997) J Clin Invest, 99, pp. 2691-2700 | ||
| 504 | |a He, S., Peng, Q., Walls, A.F., Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine (1997) J Immunol, 159, pp. 6216-6225 | ||
| 504 | |a Kaminska, R., Helisalmi, P., Harvima, R.J., Naukkarinen, A., Horsmanheimo, M., Harvima, I.T., Focal dermal-epidermal separation and fibronectin cleavage in basement membrane by human mast cell tryptase (1999) J Invest Dermatol, 113, pp. 567-573 | ||
| 504 | |a Yoshii, M., Jikuhara, A., Mori, S., Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners (2005) J Pharmacol Sci, 98, pp. 450-458 | ||
| 504 | |a Muramatsu, M., Katada, J., Hattori, M., Hayashi, I., Majima, M., Chymase mediates mast cell-induced angiogenesis in hamster sponge granulomas (2000) Eur J Pharm, 402, pp. 181-191 | ||
| 504 | |a Fang, K.C., Raymond, W.W., Blount, J.L., Caughey, G.H., Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain (1997) J Biol Chem, 272, pp. 25628-25635 | ||
| 504 | |a Theoharides, T.C., Conti, P., Mast cells: the Jekyll and Hyde of tumor growth (2004) Trends Immunol, 25, pp. 235-241 | ||
| 504 | |a Norrby, K., Mast cells and angiogenesis (2002) APMIS, 110, pp. 355-371 | ||
| 504 | |a Ibaraki, T., Muramatsu, M., Takai, S., The relationship of tryptase- and chymase-positive mast cells to angiogenesis in stage I non-small cell lung cancer (2005) Eur J Cardiothorac Surg, 28, pp. 617-621 | ||
| 504 | |a Tomita, M., Matsuzaki, Y., Onitsuka, T., Effect of mast cells on tumor angiogenesis in lung cancer (2000) Ann Thorac Surg, 69, pp. 1686-1690 | ||
| 504 | |a Welsh, T.J., Green, R.H., Richardson, D., Waller, D.A., O'Byrne, K.J., Bradding, P., Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer (2005) J Clin Oncol, 23, pp. 8959-8967 | ||
| 504 | |a Tomita, M., Matsuzaki, Y., Onitsuka, T., Correlation between mast cells and survival rates in patients with pulmonary adenocarcinoma (1999) Lung Cancer, 26, pp. 103-108 | ||
| 504 | |a Irani, A.M., Schwartz, L.B., Mast cell heterogeneity (1989) Clin Exp Allergy, 19, pp. 143-155 | ||
| 504 | |a Cabanillas-Saez, A., Schalper, J.A., Nicovani, S.M., Rudolph, M.I., Characterization of mast cells according to their content of tryptase and chymase in normal and neoplastic human uterine cervix (2002) Int J Gynecol Cancer, 12, pp. 92-98 | ||
| 504 | |a Nagata, M., Shijubo, N., Walls, A.F., Ichimiya, S., Abe, S., Sato, N., Chymase-positive mast cells in small sized adenocarcinoma of the lung (2003) Virchows Arch, 443, pp. 565-573 | ||
| 504 | |a Rajput, A.B., Turbin, D.A., Cheang, M.C., Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases (2008) Breast Cancer Res Treat, 107, pp. 249-257 | ||
| 504 | |a Nielsen, H.J., Hansen, U., Christensen, I.J., Reimert, C.M., Brunner, N., Moesgaard, F., Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue (1999) J Pathol, 189, pp. 487-495 | ||
| 504 | |a Tataroglu, C., Kargi, A., Ozkal, S., Esrefoglu, N., Akkoclu, A., Association of macrophages, mast cells and eosinophil leukocytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC) (2004) Lung Cancer, 43, pp. 47-54 | ||
| 504 | |a Dundar, E., Oner, U., Peker, B.C., Metintas, M., Isiksoy, S., Ak, G., The significance and relationship between mast cells and tumour angiogenesis in non-small cell lung carcinoma (2008) J Int Med Res, 36, pp. 88-95 | ||
| 504 | |a Nienartowicz, A., Sobaniec-Lotowska, M.E., Jarocka-Cyrta, E., Lemancewicz, D., Mast cells in neoangiogenesis (2006) Med Sci Monit, 12, pp. RA53-RA56 | ||
| 504 | |a Folkman, J., Shing, Y., Control of angiogenesis by heparin and other sulfated polysaccharides (1992) Adv Exp Med Biol, 313, pp. 355-364 | ||
| 504 | |a Powers, C.J., McLeskey, S.W., Wellstein, A., Fibroblast growth factors, their receptors and signaling (2000) Endocr Relat Cancer, 7, pp. 165-197 | ||
| 504 | |a Stack, M.S., Johnson, D.A., Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase) (1994) J Biol Chem, 269, pp. 9416-9419 | ||
| 504 | |a Coussens, L.M., Raymond, W.W., Bergers, G., Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis (1999) Genes Dev, pp. 1382-1397 | ||
| 504 | |a de Visser, K.E., Eichten, A., Coussens, L.M., Paradoxical roles of the immune system during cancer development (2006) Nat Rev Cancer, 6, pp. 24-37 | ||
| 520 | 3 | |a The impact of interstitial inflammatory cells, such as mast cells, and angiogenesis on the prognosis of cancer patients has been reported in many solid tumors, although there is disagreement about their role. We undertook a retrospective study with tissue samples from 65 patients with stage I and II non-small cell lung cancer to assess the clinical pathologic role and prognostic significance of mast cells. Mast cell phenotypes were identified by immunohistochemistry for tryptase and chymase. In addition, we identified microvessels using the endothelial marker CD34. Mast cell and microvessel density was quantified by assessing immunopositive cells in the intratumoral and peritumoral zones of tumor specimens. Both mast cell and microvessel density was higher in the peritumoral zone than the intratumoral zone (P ≤ .05). A positive correlation between mast cell (tryptase-chymase phenotype) and microvessel densities was observed in the intratumoral zone (P ≤ .05), supporting the involvement of mast cells in the angiogenic process. Regarding survival, a subset of stage I patients had a worse prognosis at five years when low mast cell (tryptase-chymase phenotype) density was found in the peritumoral zone (median survival in months [range]: 27 [1-60] versus 46 [1-60]). Multivariate Cox analysis indicated that this parameter may be an independent prognostic factor (P ≤ .05) useful for selecting candidates for earlier treatment. © 2010 Elsevier Inc. All rights reserved. |l eng | |
| 593 | |a Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires C1428EGA, Argentina | ||
| 593 | |a Hospital Italiano de Buenos Aires, Buenos Aires, C1181ACH, Argentina | ||
| 593 | |a Instituto de Oncología Ángel H. Roffo Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, C1417DTB, Argentina | ||
| 690 | 1 | 0 | |a INTRATUMORAL |
| 690 | 1 | 0 | |a LUNG CANCER |
| 690 | 1 | 0 | |a MAST CELL PHENOTYPES |
| 690 | 1 | 0 | |a MICROVESSELS |
| 690 | 1 | 0 | |a PERITUMORAL |
| 690 | 1 | 0 | |a CD34 ANTIGEN |
| 690 | 1 | 0 | |a CHYMASE |
| 690 | 1 | 0 | |a TRYPTASE |
| 690 | 1 | 0 | |a ADULT |
| 690 | 1 | 0 | |a AGED |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CANCER SURVIVAL |
| 690 | 1 | 0 | |a CELL INFILTRATION |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN TISSUE |
| 690 | 1 | 0 | |a IMMUNOHISTOCHEMISTRY |
| 690 | 1 | 0 | |a LUNG LOBECTOMY |
| 690 | 1 | 0 | |a LUNG NON SMALL CELL CANCER |
| 690 | 1 | 0 | |a MAJOR CLINICAL STUDY |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MAST CELL |
| 690 | 1 | 0 | |a MICROVASCULATURE |
| 690 | 1 | 0 | |a PHENOTYPE |
| 690 | 1 | 0 | |a PROGNOSIS |
| 690 | 1 | 0 | |a AGE FACTORS |
| 690 | 1 | 0 | |a AGED |
| 690 | 1 | 0 | |a AGED, 80 AND OVER |
| 690 | 1 | 0 | |a CARCINOMA, NON-SMALL-CELL LUNG |
| 690 | 1 | 0 | |a CHI-SQUARE DISTRIBUTION |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a IMMUNOHISTOCHEMISTRY |
| 690 | 1 | 0 | |a LUNG |
| 690 | 1 | 0 | |a LUNG NEOPLASMS |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MAST CELLS |
| 690 | 1 | 0 | |a MICROVESSELS |
| 690 | 1 | 0 | |a MIDDLE AGED |
| 690 | 1 | 0 | |a NEOPLASM STAGING |
| 690 | 1 | 0 | |a NEOVASCULARIZATION, PATHOLOGIC |
| 690 | 1 | 0 | |a PROGNOSIS |
| 690 | 1 | 0 | |a PROPORTIONAL HAZARDS MODELS |
| 690 | 1 | 0 | |a RETROSPECTIVE STUDIES |
| 690 | 1 | 0 | |a STATISTICS, NONPARAMETRIC |
| 700 | 1 | |a Dalurzo, M.C.L. | |
| 700 | 1 | |a Lastiri, J.M. | |
| 700 | 1 | |a Smith, D.E. | |
| 700 | 1 | |a Vasallo, B.C. | |
| 700 | 1 | |a Puricelli, L.I. | |
| 700 | 1 | |a Lauría de Cidre, L.S. | |
| 773 | 0 | |d 2010 |g v. 41 |h pp. 697-705 |k n. 5 |p Hum. Pathol. |x 00468177 |t Human Pathology | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/j.humpath.2009.04.029 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00468177_v41_n5_p697_Carlini |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00468177_v41_n5_p697_Carlini |y Registro en la Biblioteca Digital |
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