Principles and methods for the assessment of neurotoxicity associated with exposure to chemicals.

A detailed evaluation of the principles and methods currently used to explore the association between exposure to chemicals and the development of adverse neurobehavioural changes. Emphasis is placed on the use of animals as systems to model and predict adverse reactions in the human nervous system....

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores Corporativos: International programs on Chemical Safety, Commission of the European Communities
Formato: Libro
Lenguaje:Español
Publicado: Geneva : WHO, 1991.
Colección:Environmental health criteria ; 119
Materias:
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 01742nam a22002771a 4500
003 AR-BaBNM
005 20251014100448.0
007 ta
008 130830s1991 sz 000 0 ||||||spa d
020 |a 92-4-157119-3 
024 8 |a EUR 13222 EN 
035 |a 000162451 
040 |a AR-BaBNM  |b spa  |e aacr 
080 |a 614.7 
245 0 0 |a Principles and methods for the assessment of neurotoxicity associated with exposure to chemicals. 
260 |a Geneva :  |b WHO,  |c 1991. 
300 |a 266 p. 
490 0 |a Environmental health criteria ;  |v 119 
520 |a A detailed evaluation of the principles and methods currently used to explore the association between exposure to chemicals and the development of adverse neurobehavioural changes. Emphasis is placed on the use of animals as systems to model and predict adverse reactions in the human nervous system. The book has five sections. The first deals with general factors to be considered in the design of neurotoxicity studies and in the statistical analysis of their results. Experience acquired in the recent outbreaks of poisoning from methyl mercury and carbon disulfide are used to demonstrate both the importance of evaluating the neurotoxicity of chemicals and the power of animal studies to predict human responses. The remaining sections provide extensive information on methods developed in each of the four major research disciplines that contribute to the neurotoxic assessment of environmental chemicals. 
650 4 |a Productos químicos  |9 11094 
650 4 |a Medio ambiente  |9 8990 
650 4 |a Propiedades químicas  |9 9640 
710 2 |a International programs on Chemical Safety 
710 2 |a Commission of the European Communities 
942 |2 udc  |c LIBRO  |n 1 
999 |c 155303  |d 155303