Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierr...
Guardado en:
| Autores principales: | , , , , , , , , , |
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| Formato: | Artículo publishedVersion |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/11336/58794 http://suquia.ffyh.unc.edu.ar/handle/11336/58794 |
| Aporte de: |
| id |
I10-R181-11336-58794 |
|---|---|
| record_format |
dspace |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-181 |
| collection |
Suquía - Instituto de Antropología de Córdoba (IDACOR, CONICET y UNC) |
| language |
Inglés |
| topic |
ANCIENT DNA BIOARCHAEOLOGY TIERRA DEL FUEGO TUBERCULOSIS Paleontología Ciencias de la Tierra y relacionadas con el Medio Ambiente CIENCIAS NATURALES Y EXACTAS |
| spellingShingle |
ANCIENT DNA BIOARCHAEOLOGY TIERRA DEL FUEGO TUBERCULOSIS Paleontología Ciencias de la Tierra y relacionadas con el Medio Ambiente CIENCIAS NATURALES Y EXACTAS Guichon, Ricardo Anibal Buikstra, Jane E. Stone, Anne C. Harkins, Kelly M. Suby, Jorge Alejandro Massone, Mauricio Prieto lglesias, Alfredo Wilbur, Alicia Constantinescu, Florence Rodríguez Martín, Conrado Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| topic_facet |
ANCIENT DNA BIOARCHAEOLOGY TIERRA DEL FUEGO TUBERCULOSIS Paleontología Ciencias de la Tierra y relacionadas con el Medio Ambiente CIENCIAS NATURALES Y EXACTAS |
| description |
This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640. ±. 20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed. |
| format |
Artículo Artículo publishedVersion |
| author |
Guichon, Ricardo Anibal Buikstra, Jane E. Stone, Anne C. Harkins, Kelly M. Suby, Jorge Alejandro Massone, Mauricio Prieto lglesias, Alfredo Wilbur, Alicia Constantinescu, Florence Rodríguez Martín, Conrado |
| author_facet |
Guichon, Ricardo Anibal Buikstra, Jane E. Stone, Anne C. Harkins, Kelly M. Suby, Jorge Alejandro Massone, Mauricio Prieto lglesias, Alfredo Wilbur, Alicia Constantinescu, Florence Rodríguez Martín, Conrado |
| author_sort |
Guichon, Ricardo Anibal |
| title |
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| title_short |
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| title_full |
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| title_fullStr |
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| title_full_unstemmed |
Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence |
| title_sort |
pre-columbian tuberculosis in tierra del fuego? discussion of the paleopathological and molecular evidence |
| publisher |
Elsevier |
| publishDate |
2015 |
| url |
http://hdl.handle.net/11336/58794 http://suquia.ffyh.unc.edu.ar/handle/11336/58794 |
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