Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review
Abstract: Several scientific studies have shown contradictory results regarding the effect of probiotic supplementation on the inhibition of pro-inflammatory cytokines and the improvement of the clinical nutritional profile in people with cardiometabolic diseases. This research aimed...
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| Formato: | Artículo revista |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2021
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/34945 |
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I10-R327-article-34945 |
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Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| format |
Artículo revista |
| topic |
Probiotics Cardiometabolic diseases Inflammation biomarkers Probióticos Enfermedades cardiometabólicas Biomarcadores de inflamación . |
| spellingShingle |
Probiotics Cardiometabolic diseases Inflammation biomarkers Probióticos Enfermedades cardiometabólicas Biomarcadores de inflamación . Rivadero, ML Godoy , MM Toledo , MS Rivarola , E Perovic , NR Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| topic_facet |
Probiotics Cardiometabolic diseases Inflammation biomarkers Probióticos Enfermedades cardiometabólicas Biomarcadores de inflamación . |
| author |
Rivadero, ML Godoy , MM Toledo , MS Rivarola , E Perovic , NR |
| author_facet |
Rivadero, ML Godoy , MM Toledo , MS Rivarola , E Perovic , NR |
| author_sort |
Rivadero, ML |
| title |
Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| title_short |
Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| title_full |
Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| title_fullStr |
Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| title_full_unstemmed |
Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| title_sort |
probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review |
| description |
Abstract:
Several scientific studies have shown contradictory results regarding the effect of probiotic supplementation on the inhibition of pro-inflammatory cytokines and the improvement of the clinical nutritional profile in people with cardiometabolic diseases.
This research aimed to analyze the relationship between the intake of probiotic foods and supplements with probiotics and inflammation markers in cardiometabolic diseases in adults, through a systematic review, during the period between 2015 and 2020.
The systematic review was carried out according to the Cochrane recommendations and the GRADE guidelines; different databases such as Pubmed, Oxford and BVS were used. Three reviewers participated in this process. Papers that did not meet the quality of evidence criteria were excluded: risk of bias, imprecise results, inconsistent results, problems of applicability of the evidence, and the existence of publication bias. To control bias, the checklist proposed by Downs and Black was used. Of the 859 articles identified, 17 met the inclusion requirements. Controlled trials and randomized clinical trials were considered among the eligibility criteria.
Of all the studies that analyzed the effect of probiotics (bifidobacterium, lactobacillus, lactococcus, acetobacter) on the biomarkers of inflammation in cardiometabolic diseases, a decrease in interleukin concentrations (IL-1, IL-6, IL- 8 and IL-12) in eight of them and the same happened with TNFα; in the case of INFγ, it was decreased in one of the three studies that analyzed it; while, the consumption of probiotics caused a decrease in the concentration of hsCRP, an effect that was observed in three of six studies. According to the checklist proposed by Downs and Black, 88% of the included studies correspond to high quality and 12% to intermediate quality.
The intake of probiotics presented diverse results, being necessary more studies to identify the effect of the strains, doses and duration, in order to implement more consistent nutritional clinical treatments with the aim of improving the levels of inflammation biomarkers and risk factors in people with cardiometabolic diseases.
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| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2021 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/34945 |
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I10-R327-article-349452024-04-15T16:19:09Z Probiotic foods and their impact on biomarkers of inflammation in cardiometabolic diseases: a systematic review Alimentos probióticos y su impacto en biomarcadores de inflamación en enfermedades cardiometabólicas: una revisión sistemática A Rivadero, ML Godoy , MM Toledo , MS Rivarola , E Perovic , NR Probiotics Cardiometabolic diseases Inflammation biomarkers Probióticos Enfermedades cardiometabólicas Biomarcadores de inflamación . Abstract: Several scientific studies have shown contradictory results regarding the effect of probiotic supplementation on the inhibition of pro-inflammatory cytokines and the improvement of the clinical nutritional profile in people with cardiometabolic diseases. This research aimed to analyze the relationship between the intake of probiotic foods and supplements with probiotics and inflammation markers in cardiometabolic diseases in adults, through a systematic review, during the period between 2015 and 2020. The systematic review was carried out according to the Cochrane recommendations and the GRADE guidelines; different databases such as Pubmed, Oxford and BVS were used. Three reviewers participated in this process. Papers that did not meet the quality of evidence criteria were excluded: risk of bias, imprecise results, inconsistent results, problems of applicability of the evidence, and the existence of publication bias. To control bias, the checklist proposed by Downs and Black was used. Of the 859 articles identified, 17 met the inclusion requirements. Controlled trials and randomized clinical trials were considered among the eligibility criteria. Of all the studies that analyzed the effect of probiotics (bifidobacterium, lactobacillus, lactococcus, acetobacter) on the biomarkers of inflammation in cardiometabolic diseases, a decrease in interleukin concentrations (IL-1, IL-6, IL- 8 and IL-12) in eight of them and the same happened with TNFα; in the case of INFγ, it was decreased in one of the three studies that analyzed it; while, the consumption of probiotics caused a decrease in the concentration of hsCRP, an effect that was observed in three of six studies. According to the checklist proposed by Downs and Black, 88% of the included studies correspond to high quality and 12% to intermediate quality. The intake of probiotics presented diverse results, being necessary more studies to identify the effect of the strains, doses and duration, in order to implement more consistent nutritional clinical treatments with the aim of improving the levels of inflammation biomarkers and risk factors in people with cardiometabolic diseases. Resumen: Diversos estudios científicos han demostrado resultados contradictorios en cuanto al efecto que tiene la suplementación con probióticos sobre la inhibición de citoquinas proinflamatorias y la mejora del perfil clínico nutricional en personas con enfermedades cardiometabólicas. Esta investigación tuvo como objetivo analizar la relación entre la ingesta de alimentos probióticos y suplementos con probióticos y marcadores de inflamación en enfermedades cardiometabólicas en personas adultas, a través de una revisión sistemática, durante el período comprendido entre 2015 y 2020. La revisión sistemática se realizó de acuerdo a las recomendaciones Cochrane y las guías GRADE; se utilizaron diferentes bases de datos como Pubmed, Oxford y BVS. Participaron de este proceso tres revisores. Se excluyeron los trabajos que no cumplian con los criterios de calidad de la evidencia: riesgo de sesgo, resultados imprecisos, resultados inconsistentes, problemas de aplicabilidad de la evidencia y la existencia de sesgo de publicación. Para el control del sesgo se utilizó la lista de verificación propuesta por Downs y Black. De los 859 artículos identificados, 17 cumplieron los requisitos de inclusión. Entre los criterios de elegibilidad se consideraron los ensayos controlados y ensayos clínicos aleatorizados. Del total de los estudios que analizaron el efecto de los probióticos (bifidobacterium, lactobacillus, lactococcus, acetobacter) sobre los biomarcadores de inflamación en enfermedades cardiometabólicas, se evidenció una disminución de las concentraciones de interleucinas (IL-1, IL-6, IL-8 e IL-12) en ocho de ellos, lo mismo sucedió con el FNTα; en el caso del IFNγ se vio disminuido en uno de tres estudios que lo analizaron; mientras que, el consumo de probióticos provocó el descenso de la concentración de PCRus, efecto que se observó en tres de seis estudios. Según la lista de verificación propuesta por Downs y Black, el 88% de los estudios incluidos corresponde a calidad alta y el 12% a calidad intermedia. La ingesta de probióticos presentó resultados diversos, siendo necesarios más estudios para identificar el efecto de las cepas, dosis y duración, a fin de poder implementar tratamientos clínicos nutricionales más consistentes con el objetivo de mejorar los niveles de biomarcadores de inflamación y los factores de riesgo en personas con enfermedades cardiometabólicas. . Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-10-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto texto https://revistas.unc.edu.ar/index.php/med/article/view/34945 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 78 No. Suplemento (2021): Suplemento JIC XXII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 78 Núm. Suplemento (2021): Suplemento JIC XXII Revista da Faculdade de Ciências Médicas de Córdoba; v. 78 n. Suplemento (2021): Suplemento JIC XXII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0 |