Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba

In Argentina, colorectal cancer (CRC) is the second most common cancer in terms of incidence and mortality (12.2% of the total). Early diagnosis (pre-neoplastic lesions and stage 0) allows a 90% survival rate. To encourage early detection of CRC in Cordoba, a pilot experience (PE) populatio...

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Autores principales: Butinof , M, Musali , R, Mariani , ML, Aparicio , ML, Alonso , D
Formato: Artículo revista
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
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Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/38940
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id I10-R327-article-38940
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
format Artículo revista
topic colorectal neoplasms
Epidemiological Monitoring
Mass Screening
CANCER COLORRECTAL
Vigilancia epidemiológica
Tamizaje
.
spellingShingle colorectal neoplasms
Epidemiological Monitoring
Mass Screening
CANCER COLORRECTAL
Vigilancia epidemiológica
Tamizaje
.
Butinof , M
Musali , R
Mariani , ML
Aparicio , ML
Alonso , D
Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
topic_facet colorectal neoplasms
Epidemiological Monitoring
Mass Screening
CANCER COLORRECTAL
Vigilancia epidemiológica
Tamizaje
.
author Butinof , M
Musali , R
Mariani , ML
Aparicio , ML
Alonso , D
author_facet Butinof , M
Musali , R
Mariani , ML
Aparicio , ML
Alonso , D
author_sort Butinof , M
title Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
title_short Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
title_full Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
title_fullStr Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
title_full_unstemmed Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba
title_sort colorectal cancer prevention through population screening: target group risk profiles. department of pocho, province of córdoba
description In Argentina, colorectal cancer (CRC) is the second most common cancer in terms of incidence and mortality (12.2% of the total). Early diagnosis (pre-neoplastic lesions and stage 0) allows a 90% survival rate. To encourage early detection of CRC in Cordoba, a pilot experience (PE) population-based screening using a fecal immunochemical test (iFOBT) among adults aged 50 to 75 years, was designed by the Ministry of Health of the Province; taking place in the Department of Pocho (2018–2019). Objectives: to describe the sociodemographic characteristics and lifestyle habits of PE participants and to identify risk profiles associated with the iFOBT result and risk group: average (AR) or elevated (ER). The results of the iFOBT and interviews conducted during the implementation of the project were analyzed. Simple descriptive statistics, χ² test, multiple correspondence analysis (MCA), and logistic regressions were calculated. A total of 265 individuals participated (49.8% women), 19.6% ER and 80.4% AR; positivity rate of the test=19.3%. According to the MCA, the ER group was characterized by obesity, elevated glucose, blood pressure and cholesterol, and no physical activity; while the AR group was characterized by physical activity, eutrophic Body Mass Index and low educational level (EL). Regarding ER, consuming grilled meat was a protective factor (PF) (OR=0.30 - IC95% 0.10-0.86), and being obese was a risk factor (RF) (OR=3.82 - IC95% 1.03-14.08). The iFOBT+ group was characterized by being formed by males, ≤60 years old, with low EL and without health coverage (HC); the iFOBTi- group by being formed by females, ≥60 years old, overweight, HC, and complete secondary school. Regarding the iFOBT outcome, the female sex was a PF (OR=0.13 -IC95% 0.04-0.54) and low EL a RF (OR=8.02-IC95% 1.71-37.56).  This PE allowed us to characterize a population of adults in an area with low accessibility to the health system, to identify a high burden of morbidity potentially associated with CRC, and to install a screening program with high acceptance, laying the groundwork for future actions.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/med/article/view/38940
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first_indexed 2024-09-03T21:03:46Z
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spelling I10-R327-article-389402024-04-15T16:14:45Z Colorectal Cancer prevention through population screening: target group risk profiles. Department of Pocho, Province of Córdoba Prevención del cáncer colorrectal mediante tamizaje poblacional: perfiles de riesgo de la población objetivo. Departamento de Pocho, Provincia de Córdoba . Butinof , M Musali , R Mariani , ML Aparicio , ML Alonso , D colorectal neoplasms Epidemiological Monitoring Mass Screening CANCER COLORRECTAL Vigilancia epidemiológica Tamizaje . In Argentina, colorectal cancer (CRC) is the second most common cancer in terms of incidence and mortality (12.2% of the total). Early diagnosis (pre-neoplastic lesions and stage 0) allows a 90% survival rate. To encourage early detection of CRC in Cordoba, a pilot experience (PE) population-based screening using a fecal immunochemical test (iFOBT) among adults aged 50 to 75 years, was designed by the Ministry of Health of the Province; taking place in the Department of Pocho (2018–2019). Objectives: to describe the sociodemographic characteristics and lifestyle habits of PE participants and to identify risk profiles associated with the iFOBT result and risk group: average (AR) or elevated (ER). The results of the iFOBT and interviews conducted during the implementation of the project were analyzed. Simple descriptive statistics, χ² test, multiple correspondence analysis (MCA), and logistic regressions were calculated. A total of 265 individuals participated (49.8% women), 19.6% ER and 80.4% AR; positivity rate of the test=19.3%. According to the MCA, the ER group was characterized by obesity, elevated glucose, blood pressure and cholesterol, and no physical activity; while the AR group was characterized by physical activity, eutrophic Body Mass Index and low educational level (EL). Regarding ER, consuming grilled meat was a protective factor (PF) (OR=0.30 - IC95% 0.10-0.86), and being obese was a risk factor (RF) (OR=3.82 - IC95% 1.03-14.08). The iFOBT+ group was characterized by being formed by males, ≤60 years old, with low EL and without health coverage (HC); the iFOBTi- group by being formed by females, ≥60 years old, overweight, HC, and complete secondary school. Regarding the iFOBT outcome, the female sex was a PF (OR=0.13 -IC95% 0.04-0.54) and low EL a RF (OR=8.02-IC95% 1.71-37.56).  This PE allowed us to characterize a population of adults in an area with low accessibility to the health system, to identify a high burden of morbidity potentially associated with CRC, and to install a screening program with high acceptance, laying the groundwork for future actions. En Argentina el Cáncer Colorrectal (CCR) es el segundo en incidencia y mortalidad (12,2% del total). El diagnóstico temprano (lesiones pre-neoplásicas y estadío 0), permite una sobrevida del 90%. A fin de promover la detección temprana del CCR en Córdoba, el Ministerio de Salud provincial diseñó una experiencia piloto (EP) de tamizaje poblacional mediante Test Inmunoquímico de Sangre Oculta en Materia Fecal (TSOMFi), entre adultos de 50 a 75 años del Departamento de Pocho (2018-2019). Objetivos: describir las características sociodemográficas y hábitos de vida de las/os participantes en la EP e identificar perfiles de riesgo asociados al resultado del TSOMFi y al grupo de riesgo, promedio (RP) o elevado (RE). Se analizaron los resultados del TSOMFi y entrevistas realizadas durante su implementación. Se calcularon estadísticas descriptivas simples, test χ², análisis factorial de correspondencias múltiples (AFCM) y regresiones logísticas. Participaron 265 personas, (49,8% mujeres), 19,6% RE y 80,4% RP, tasa de positividad del test=19,3%. Según el AFCM, el grupo de RE se caracterizó por presentar obesidad, glucemia, tensión arterial y colesterol elevados y no realizar actividad física; y el de RP por realizar actividad física, presentar Índice de Masa Corporal eutrófico y bajo nivel de instrucción (NI). Con respecto al RE, consumir carne asada fue un factor de protección (FP); (OR=0,30 -IC95% 0,10-0,86) y ser obesas/os, un factor de riesgo (FR) (OR=3,82 IC95% 1,03-14,08). El grupo con TSOMFi+ se caracterizó por estar integrado por varones, ≤60 años, con bajo NI y sin cobertura de salud (CS); el grupo con TSOMFi- por estar integrado por mujeres, ≥60 años, con sobrepeso, CS y secundario completo. Respecto al resultado del TSOMFi, el sexo femenino fue un FP (OR=0,13 -IC95% 0,04-0,54) y el bajo NI un FR (OR=8,02-IC95% 1,71-37,56). Este EP permitió caracterizar una población de adultos de una zona de baja accesibilidad al sistema de salud, identificar una alta carga de morbilidad potencialmente asociada al CCR e instalar un programa de tamizaje con alta aceptación, sentando bases para acciones futuras.   . Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-10-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto . https://revistas.unc.edu.ar/index.php/med/article/view/38940 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. Suplemento JIC XXIII (2022): Suplemento JIC XXIII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0