Virgin olive oil reduces blood pressure in hypertensive elderly subjects

Background and aims: Hypertension is one of the most important risk factors for coronary heart disease. Recent studies have pointed out the possibility that virgin olive oil may lower blood pressure in hypertensive subjects. However, until the date there is scarce information regarding elderly peopl...

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Autores principales: Perona, Javier S., Cañizares, Julio, Montero, Emilio, Sánchez Dominguez, José M., Catalá, Ángel, Ruiz Gutiérrez, Valentina
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2004
Materias:
Ciencias Médicas
Virgin olive oil
Elderly
Hypertension
Cholesterol
Tocopherol
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/127884
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-127884
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Virgin olive oil
Elderly
Hypertension
Cholesterol
Tocopherol
spellingShingle Ciencias Médicas
Virgin olive oil
Elderly
Hypertension
Cholesterol
Tocopherol
Perona, Javier S.
Cañizares, Julio
Montero, Emilio
Sánchez Dominguez, José M.
Catalá, Ángel
Ruiz Gutiérrez, Valentina
Virgin olive oil reduces blood pressure in hypertensive elderly subjects
topic_facet Ciencias Médicas
Virgin olive oil
Elderly
Hypertension
Cholesterol
Tocopherol
description Background and aims: Hypertension is one of the most important risk factors for coronary heart disease. Recent studies have pointed out the possibility that virgin olive oil may lower blood pressure in hypertensive subjects. However, until the date there is scarce information regarding elderly people. The present study was designed to assess the effect of dietary virgin olive oil on blood pressure in medically-treated hypertensive elderly patients. Methods: 31 medically-treated hypertensive (HT) elderly patients and 31 normotensive (NT) elderly volunteers participated in a randomized sequential dietary intervention. Subjects consumed diets enriched in sunflower oil (SO) or virgin olive oil (VOO) for four weeks each with a four-week washout period between them. Results: VOO reduced total and LDL-cholesterol in NT but not in HT (p<0.01) and the concentrations were lower than in the group consuming SO. In contrast, no significant differences were found in the levels of tocopherols among the groups studied. Ironinduced oxidation of LDL resulted in a complete loss of monoacylglycerols (MG) and diacylglycerols (DG) and a reduction in triacylglycerols (TG) (60-80%), which was found to be greater in HT (p<0.01) with no effect of diet. VOO consumption normalized systolic pressure in the HT group (136 ± 10 mmHg) compared to SO (150 ± 8 mmHg). Conclusion: dietary VOO proved to be helpful in reducing the systolic pressure of treated HT elderly subjects. However, a greater resistance to the lowering effect of VOO of total and LDL-cholesterol and a greater susceptibility to TG oxidation was detected in these patients.
format Articulo
Preprint
author Perona, Javier S.
Cañizares, Julio
Montero, Emilio
Sánchez Dominguez, José M.
Catalá, Ángel
Ruiz Gutiérrez, Valentina
author_facet Perona, Javier S.
Cañizares, Julio
Montero, Emilio
Sánchez Dominguez, José M.
Catalá, Ángel
Ruiz Gutiérrez, Valentina
author_sort Perona, Javier S.
title Virgin olive oil reduces blood pressure in hypertensive elderly subjects
title_short Virgin olive oil reduces blood pressure in hypertensive elderly subjects
title_full Virgin olive oil reduces blood pressure in hypertensive elderly subjects
title_fullStr Virgin olive oil reduces blood pressure in hypertensive elderly subjects
title_full_unstemmed Virgin olive oil reduces blood pressure in hypertensive elderly subjects
title_sort virgin olive oil reduces blood pressure in hypertensive elderly subjects
publishDate 2004
url http://sedici.unlp.edu.ar/handle/10915/127884
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