A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems

Current clinical data show a strong correlation between time of day and illness manifestation or immune activity. For example, symptoms of rheumatoid arthritis occur during the morning (Katz et al. 2002) most asthma attacks during the night (Reinberg 2006), and the effects of immunization also chang...

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Autores principales: Leone, María Juliana, Chiesa, Juan José, Marpegan, Luciano, Golombek, Diego Andrés
Formato: Articulo Revision
Lenguaje:Inglés
Publicado: 2007
Materias:
Ciencias Médicas
Circadian clock
Immune system
Strong regulation
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/147324
https://pmr.safisiol.org.ar/wp-content/uploads/2022/08/vol2_n10_may.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-147324
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Circadian clock
Immune system
Strong regulation
spellingShingle Ciencias Médicas
Circadian clock
Immune system
Strong regulation
Leone, María Juliana
Chiesa, Juan José
Marpegan, Luciano
Golombek, Diego Andrés
A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
topic_facet Ciencias Médicas
Circadian clock
Immune system
Strong regulation
description Current clinical data show a strong correlation between time of day and illness manifestation or immune activity. For example, symptoms of rheumatoid arthritis occur during the morning (Katz et al. 2002) most asthma attacks during the night (Reinberg 2006), and the effects of immunization also change with daytime (Langlois et al. 1995). Taken together, these reports suggest a strong regulation exerted by the circadian clock on the immune system, which will be reviewed in this article. Moreover, clock-controlled rhythms in several variables exert a feedback regulation on the circadian oscillator itself, a mechanism that we shall also consider in this paper.
format Articulo
Revision
author Leone, María Juliana
Chiesa, Juan José
Marpegan, Luciano
Golombek, Diego Andrés
author_facet Leone, María Juliana
Chiesa, Juan José
Marpegan, Luciano
Golombek, Diego Andrés
author_sort Leone, María Juliana
title A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
title_short A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
title_full A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
title_fullStr A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
title_full_unstemmed A time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
title_sort time to kill, and a time to heal: pathophysiological interactions between the circadian and the immune systems
publishDate 2007
url http://sedici.unlp.edu.ar/handle/10915/147324
https://pmr.safisiol.org.ar/wp-content/uploads/2022/08/vol2_n10_may.pdf
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