Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment

There is currently high interest in developing nanofluidic devices whose iontronic output is defined by biological interactions. The fabrication of a phosphate responsive nanofluidic diode by using the biological relevant amine–phosphate interactions is shown. The fabrication procedure includes the...

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Autores principales: Pérez Mitta, Gonzalo, Marmisollé, Waldemar Alejandro, Albesa, Alberto Gustavo, Toimil Molares, María Eugenia, Trautmann, Christina, Azzaroni, Omar
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
Materias:
Ciencias Exactas
Química
biosensing
iontronics
nanofluidics
solid-state nanopores
supramolecular chemistry
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/151350
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-151350
record_format dspace
spelling I19-R120-10915-1513502023-04-13T04:06:45Z http://sedici.unlp.edu.ar/handle/10915/151350 issn:1613-6810 Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment Pérez Mitta, Gonzalo Marmisollé, Waldemar Alejandro Albesa, Alberto Gustavo Toimil Molares, María Eugenia Trautmann, Christina Azzaroni, Omar 2018-05 2023-04-12T14:51:47Z en Ciencias Exactas Química biosensing iontronics nanofluidics solid-state nanopores supramolecular chemistry There is currently high interest in developing nanofluidic devices whose iontronic output is defined by biological interactions. The fabrication of a phosphate responsive nanofluidic diode by using the biological relevant amine–phosphate interactions is shown. The fabrication procedure includes the modification of a track-etched asymmetric (conical) nanochannel with polyallylamine (PAH) by electrostatic self-assembly. PAH is the arcaetypical model of polyamine and it is further used to address the nanochannels with phosphate responsivity. In order to explore the influence that phosphate in solution has in the conductance of the modified nanochannels, current–voltage measurements using different concentrations of phosphates are performed. Furthermore, to have a complete physicochemical understanding of the system, experimental data is analyzed using a continuous model based on Poison–Nernst–Planck equations and compared with results obtained from stochastic Monte Carlo simulations. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas Articulo Articulo http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) application/pdf
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Química
biosensing
iontronics
nanofluidics
solid-state nanopores
supramolecular chemistry
spellingShingle Ciencias Exactas
Química
biosensing
iontronics
nanofluidics
solid-state nanopores
supramolecular chemistry
Pérez Mitta, Gonzalo
Marmisollé, Waldemar Alejandro
Albesa, Alberto Gustavo
Toimil Molares, María Eugenia
Trautmann, Christina
Azzaroni, Omar
Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
topic_facet Ciencias Exactas
Química
biosensing
iontronics
nanofluidics
solid-state nanopores
supramolecular chemistry
description There is currently high interest in developing nanofluidic devices whose iontronic output is defined by biological interactions. The fabrication of a phosphate responsive nanofluidic diode by using the biological relevant amine–phosphate interactions is shown. The fabrication procedure includes the modification of a track-etched asymmetric (conical) nanochannel with polyallylamine (PAH) by electrostatic self-assembly. PAH is the arcaetypical model of polyamine and it is further used to address the nanochannels with phosphate responsivity. In order to explore the influence that phosphate in solution has in the conductance of the modified nanochannels, current–voltage measurements using different concentrations of phosphates are performed. Furthermore, to have a complete physicochemical understanding of the system, experimental data is analyzed using a continuous model based on Poison–Nernst–Planck equations and compared with results obtained from stochastic Monte Carlo simulations.
format Articulo
Articulo
author Pérez Mitta, Gonzalo
Marmisollé, Waldemar Alejandro
Albesa, Alberto Gustavo
Toimil Molares, María Eugenia
Trautmann, Christina
Azzaroni, Omar
author_facet Pérez Mitta, Gonzalo
Marmisollé, Waldemar Alejandro
Albesa, Alberto Gustavo
Toimil Molares, María Eugenia
Trautmann, Christina
Azzaroni, Omar
author_sort Pérez Mitta, Gonzalo
title Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
title_short Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
title_full Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
title_fullStr Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
title_full_unstemmed Phosphate-Responsive Biomimetic Nanofluidic Diodes Regulated by Polyamine–Phosphate Interactions: Insights into Their Functional Behavior from Theory and Experiment
title_sort phosphate-responsive biomimetic nanofluidic diodes regulated by polyamine–phosphate interactions: insights into their functional behavior from theory and experiment
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/151350
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AT toimilmolaresmariaeugenia phosphateresponsivebiomimeticnanofluidicdiodesregulatedbypolyaminephosphateinteractionsinsightsintotheirfunctionalbehaviorfromtheoryandexperiment
AT trautmannchristina phosphateresponsivebiomimeticnanofluidicdiodesregulatedbypolyaminephosphateinteractionsinsightsintotheirfunctionalbehaviorfromtheoryandexperiment
AT azzaroniomar phosphateresponsivebiomimeticnanofluidicdiodesregulatedbypolyaminephosphateinteractionsinsightsintotheirfunctionalbehaviorfromtheoryandexperiment
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