Emulsan, a tailorable biopolymer for controlled release

Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating ag...

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Autores principales: Castro, Guillermo Raúl, Panilaitis, Bruce, Kaplan, David L.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2008
Materias:
Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/152994
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-152994
record_format dspace
spelling I19-R120-10915-1529942023-05-16T04:06:35Z http://sedici.unlp.edu.ar/handle/10915/152994 issn:0960-8524 issn:1873-2976 Emulsan, a tailorable biopolymer for controlled release Castro, Guillermo Raúl Panilaitis, Bruce Kaplan, David L. 2008 2023-05-15T15:13:21Z en Bioquímica Emulsan Bioemulsifier Controlled release Agriculture Fermentation Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest. Centro de Investigación y Desarrollo en Fermentaciones Industriales Articulo Articulo http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
spellingShingle Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
Castro, Guillermo Raúl
Panilaitis, Bruce
Kaplan, David L.
Emulsan, a tailorable biopolymer for controlled release
topic_facet Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
description Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest.
format Articulo
Articulo
author Castro, Guillermo Raúl
Panilaitis, Bruce
Kaplan, David L.
author_facet Castro, Guillermo Raúl
Panilaitis, Bruce
Kaplan, David L.
author_sort Castro, Guillermo Raúl
title Emulsan, a tailorable biopolymer for controlled release
title_short Emulsan, a tailorable biopolymer for controlled release
title_full Emulsan, a tailorable biopolymer for controlled release
title_fullStr Emulsan, a tailorable biopolymer for controlled release
title_full_unstemmed Emulsan, a tailorable biopolymer for controlled release
title_sort emulsan, a tailorable biopolymer for controlled release
publishDate 2008
url http://sedici.unlp.edu.ar/handle/10915/152994
work_keys_str_mv AT castroguillermoraul emulsanatailorablebiopolymerforcontrolledrelease
AT panilaitisbruce emulsanatailorablebiopolymerforcontrolledrelease
AT kaplandavidl emulsanatailorablebiopolymerforcontrolledrelease
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