Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers

New technologies and sterilization agents for heat-sensitive materials are under intense investigation. Plasma sterilization, an atoxic low-temperature substitute for conventional sterilization, uses various gases that are activated by an electrical discharge, generating reactive species that promot...

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Detalles Bibliográficos
Autores principales: Oliveira, Débora M. F., Kikuchi, Irene S., Moreira, Adir J., Silva, Juliano M. F., Pinto, Terezinha J. A., Mansano, Ronaldo D.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Monitoreo Fisiológico
biological monitor; inductively coupled plasma; medical devices; microbial efficacy; plasma sterilization; reactive ion etching
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18100
http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_1_13.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-18100
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Monitoreo Fisiológico
biological monitor; inductively coupled plasma; medical devices; microbial efficacy; plasma sterilization; reactive ion etching
spellingShingle Farmacia
Monitoreo Fisiológico
biological monitor; inductively coupled plasma; medical devices; microbial efficacy; plasma sterilization; reactive ion etching
Oliveira, Débora M. F.
Kikuchi, Irene S.
Moreira, Adir J.
Silva, Juliano M. F.
Pinto, Terezinha J. A.
Mansano, Ronaldo D.
Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
topic_facet Farmacia
Monitoreo Fisiológico
biological monitor; inductively coupled plasma; medical devices; microbial efficacy; plasma sterilization; reactive ion etching
description New technologies and sterilization agents for heat-sensitive materials are under intense investigation. Plasma sterilization, an atoxic low-temperature substitute for conventional sterilization, uses various gases that are activated by an electrical discharge, generating reactive species that promote lethality in microorganisms. Here, assays were performed using pure O2 and O2 + H2O2 mixture gas plasmas against a standard load of Bacillus atrophaeus spores inoculated on glass carriers inside PVC catheters. The sterilization efficiency was studied as a function of plasma system (reactive ion etching or inductively coupled plasma), biological monitor lumen diameter, gas, radio frequency power, and sub-lethal exposition time. After sterilization, the biological monitors were disassembled and the surviving bacteria were grown in trypticase soy broth using the most probable number technique. Plasma antimicrobial activity depended on the catheter’s internal diameter and radio frequency powers. The O2 + H2O2 mixture exhibited higher microbial efficacy than pure O2 in both plasma systems.
format Articulo
Articulo
author Oliveira, Débora M. F.
Kikuchi, Irene S.
Moreira, Adir J.
Silva, Juliano M. F.
Pinto, Terezinha J. A.
Mansano, Ronaldo D.
author_facet Oliveira, Débora M. F.
Kikuchi, Irene S.
Moreira, Adir J.
Silva, Juliano M. F.
Pinto, Terezinha J. A.
Mansano, Ronaldo D.
author_sort Oliveira, Débora M. F.
title Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
title_short Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
title_full Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
title_fullStr Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
title_full_unstemmed Evaluation of Microbicidal Activity of Oxygen-Containing Plasmas using Biological Monitors with Different Lumen Calibers
title_sort evaluation of microbicidal activity of oxygen-containing plasmas using biological monitors with different lumen calibers
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/18100
http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_1_13.pdf
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