Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning

The adsorption of certain metal ions and dyes on powdered seeds (pits) of Phoenix sylvestris (Arecaceae) suggests the investigation of such material for the adsorption of oral poisoning substances from the gastrointestinal tract. Therefore, the present study was undertaken to prepare different types...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad N., Hussain, Khalid, Bukhari, Nadeem I., Latif, Abida, Hashmi, Furqan K., Hussain, Amjad, Karim, Sabiha, Islam, Muhammad, Masood, Muhammad
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/20218
http://www.latamjpharm.org/resumenes/31/5/LAJOP_31_5_1_6.pdf
Aporte de:
id I19-R120-10915-20218
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Adsorption capacity
Equilibrium contact time
Paracetamol poisoning
Phoenix sylvestris pits
Semillas
Envenenamiento
spellingShingle Farmacia
Adsorption capacity
Equilibrium contact time
Paracetamol poisoning
Phoenix sylvestris pits
Semillas
Envenenamiento
Khan, Muhammad N.
Hussain, Khalid
Bukhari, Nadeem I.
Latif, Abida
Hashmi, Furqan K.
Hussain, Amjad
Karim, Sabiha
Islam, Muhammad
Masood, Muhammad
Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
topic_facet Farmacia
Adsorption capacity
Equilibrium contact time
Paracetamol poisoning
Phoenix sylvestris pits
Semillas
Envenenamiento
description The adsorption of certain metal ions and dyes on powdered seeds (pits) of Phoenix sylvestris (Arecaceae) suggests the investigation of such material for the adsorption of oral poisoning substances from the gastrointestinal tract. Therefore, the present study was undertaken to prepare different types of adsorbents from date pits and explore their adsorption capacity for paracetamol at two physiological conditions, enzyme free simulated gastric and intestinal fluids. The activated charcoal was used as a control. The equilibrium contact time, determined by combining the three forms of date pits and activated charcoal separately with paracetamol in a ratio of 15:1 w/w in both the fluids, was found to be 60 min. The adsorption of all the adsorbents for paracetamol was investigated by increasing the amount of adsorbents while keeping the amount of adsorbate fix, and the data obtained was found to be fit in the Langmuir isotherm. The bonding constants of all the adsorbents were significantly different in SGF (p < 0.05), whereas not significantly different in SIF. The adsorption capacities of all the adsorbents were not significantly different in SGF, whereas, significantly different in SIF (p < 0.05). The results of this study indicate that date pits may be used to prepare activated carbon that may serve as an economical adsorbent for the management of paracetamol oral poisoning cases.
format Articulo
Articulo
author Khan, Muhammad N.
Hussain, Khalid
Bukhari, Nadeem I.
Latif, Abida
Hashmi, Furqan K.
Hussain, Amjad
Karim, Sabiha
Islam, Muhammad
Masood, Muhammad
author_facet Khan, Muhammad N.
Hussain, Khalid
Bukhari, Nadeem I.
Latif, Abida
Hashmi, Furqan K.
Hussain, Amjad
Karim, Sabiha
Islam, Muhammad
Masood, Muhammad
author_sort Khan, Muhammad N.
title Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
title_short Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
title_full Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
title_fullStr Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
title_full_unstemmed Evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
title_sort evaluation of seeds of phoenix sylvestris as novel candidate adsorbent in paracetamol poisoning
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/20218
http://www.latamjpharm.org/resumenes/31/5/LAJOP_31_5_1_6.pdf
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