Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals

Ferula hermonis (Apiaceae) is a well known Middle-Eastern medicinal plant. It has long been used traditionally as an aphrodisiac agent. The antinociceptive and anti-inflammatory activities of the root oil of F. hermonis were evaluated by the hot-plate test, the acetic acid-induced writhing test and...

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Detalles Bibliográficos
Autores principales:	Geroushi, Afaf, Auzi, Abdurazag A., Elhwuegi, Abdalla S., Elzawam, Fawzi, El-Sherif, Akram, Nahar, Lutfun, Sarker, Satyajit D.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia anti-inflammatory; antinociceptive; apiaceae; carrageenan-induced edema; ferula hermonis; hot plate test
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8085 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_2.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8085
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia anti-inflammatory; antinociceptive; apiaceae; carrageenan-induced edema; ferula hermonis; hot plate test
spellingShingle	Farmacia anti-inflammatory; antinociceptive; apiaceae; carrageenan-induced edema; ferula hermonis; hot plate test Geroushi, Afaf Auzi, Abdurazag A. Elhwuegi, Abdalla S. Elzawam, Fawzi El-Sherif, Akram Nahar, Lutfun Sarker, Satyajit D. Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
topic_facet	Farmacia anti-inflammatory; antinociceptive; apiaceae; carrageenan-induced edema; ferula hermonis; hot plate test
description	Ferula hermonis (Apiaceae) is a well known Middle-Eastern medicinal plant. It has long been used traditionally as an aphrodisiac agent. The antinociceptive and anti-inflammatory activities of the root oil of F. hermonis were evaluated by the hot-plate test, the acetic acid-induced writhing test and the carragennan-induced rat paw edema test. In the hot-plate test, the root oil in oral doses of 400 and 800 mg/kg significantly increased the reaction time of animals to thermal pain, and in the acetic acid-induced writhing test, in similar oral doses it showed a considerable inhibition of acetic acid-induced writhing in mice in a dose-dependant manner. In the carrageenan induced paw oedema model, the oral administration of 50 and 100 mg/kg of F. hermonis root oil to adult Wister rats showed a statistically significant decrease in rat paw o induced by carrageenan 1 and 2 h after carrageenan injection.
format	Articulo Comunicacion
author	Geroushi, Afaf Auzi, Abdurazag A. Elhwuegi, Abdalla S. Elzawam, Fawzi El-Sherif, Akram Nahar, Lutfun Sarker, Satyajit D.
author_facet	Geroushi, Afaf Auzi, Abdurazag A. Elhwuegi, Abdalla S. Elzawam, Fawzi El-Sherif, Akram Nahar, Lutfun Sarker, Satyajit D.
author_sort	Geroushi, Afaf
title	Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
title_short	Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
title_full	Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
title_fullStr	Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
title_full_unstemmed	Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
title_sort	antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/8085 http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_2_2.pdf
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Antinociceptive and anti-inflammatory activity of ferula hermonis root oil in experimental animals

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