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spelling I28-R145-paper_00145793_v586_n19_p2991_Alleva_oai2024-08-16 Alleva, K. Chara, O. Amodeo, G. 2012 Osmolarity not only plays a key role in celluar homeostasis but also challenges cell survival. The molecular understanding of osmosis has not yet been completely achieved, and the discovery of aquaporins as molecular entities involved in water transport has caused osmosis to again become a focus of research. The main questions that need to be answered are the mechanism underlying the osmotic permeability coefficients and the extent to which aquaporins change our understanding of osmosis. Here, attempts to answer these questions are discussed. Critical aspects of the state of the state of knowledge on osmosis, a topic that has been studied since 19th century, are reviewed and integrated with the available information provided by in vivo, in vitro and in silico approaches. © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. application/pdf http://hdl.handle.net/20.500.12110/paper_00145793_v586_n19_p2991_Alleva info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar FEBS Lett. 2012;586(19):2991-2999 Aquaporin Osmosis Osmotic permeability Phenomenological law Water transport aquaporin bioinformatics biophysics brain edema hydraulic permeability lipid bilayer membrane permeability molecular interaction nonhuman nutrient uptake osmosis plant physiology priority journal protein function protein structure review statistical analysis transport kinetics tumor growth tumor vascularization water transport Animals Aquaporins Biophysical Phenomena Cell Membrane Permeability Computational Biology History, 20th Century History, 21st Century Humans Models, Biological Osmolar Concentration Osmosis Plant Proteins Water Aquaporins: Another piece in the osmotic puzzle info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00145793_v586_n19_p2991_Alleva_oai
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-145
collection Repositorio Digital de la Universidad de Buenos Aires (UBA)
topic Aquaporin
Osmosis
Osmotic permeability
Phenomenological law
Water transport
aquaporin
bioinformatics
biophysics
brain edema
hydraulic permeability
lipid bilayer
membrane permeability
molecular interaction
nonhuman
nutrient uptake
osmosis
plant physiology
priority journal
protein function
protein structure
review
statistical analysis
transport kinetics
tumor growth
tumor vascularization
water transport
Animals
Aquaporins
Biophysical Phenomena
Cell Membrane Permeability
Computational Biology
History, 20th Century
History, 21st Century
Humans
Models, Biological
Osmolar Concentration
Osmosis
Plant Proteins
Water
spellingShingle Aquaporin
Osmosis
Osmotic permeability
Phenomenological law
Water transport
aquaporin
bioinformatics
biophysics
brain edema
hydraulic permeability
lipid bilayer
membrane permeability
molecular interaction
nonhuman
nutrient uptake
osmosis
plant physiology
priority journal
protein function
protein structure
review
statistical analysis
transport kinetics
tumor growth
tumor vascularization
water transport
Animals
Aquaporins
Biophysical Phenomena
Cell Membrane Permeability
Computational Biology
History, 20th Century
History, 21st Century
Humans
Models, Biological
Osmolar Concentration
Osmosis
Plant Proteins
Water
Alleva, K.
Chara, O.
Amodeo, G.
Aquaporins: Another piece in the osmotic puzzle
topic_facet Aquaporin
Osmosis
Osmotic permeability
Phenomenological law
Water transport
aquaporin
bioinformatics
biophysics
brain edema
hydraulic permeability
lipid bilayer
membrane permeability
molecular interaction
nonhuman
nutrient uptake
osmosis
plant physiology
priority journal
protein function
protein structure
review
statistical analysis
transport kinetics
tumor growth
tumor vascularization
water transport
Animals
Aquaporins
Biophysical Phenomena
Cell Membrane Permeability
Computational Biology
History, 20th Century
History, 21st Century
Humans
Models, Biological
Osmolar Concentration
Osmosis
Plant Proteins
Water
description Osmolarity not only plays a key role in celluar homeostasis but also challenges cell survival. The molecular understanding of osmosis has not yet been completely achieved, and the discovery of aquaporins as molecular entities involved in water transport has caused osmosis to again become a focus of research. The main questions that need to be answered are the mechanism underlying the osmotic permeability coefficients and the extent to which aquaporins change our understanding of osmosis. Here, attempts to answer these questions are discussed. Critical aspects of the state of the state of knowledge on osmosis, a topic that has been studied since 19th century, are reviewed and integrated with the available information provided by in vivo, in vitro and in silico approaches. © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
format Artículo
Artículo
publishedVersion
author Alleva, K.
Chara, O.
Amodeo, G.
author_facet Alleva, K.
Chara, O.
Amodeo, G.
author_sort Alleva, K.
title Aquaporins: Another piece in the osmotic puzzle
title_short Aquaporins: Another piece in the osmotic puzzle
title_full Aquaporins: Another piece in the osmotic puzzle
title_fullStr Aquaporins: Another piece in the osmotic puzzle
title_full_unstemmed Aquaporins: Another piece in the osmotic puzzle
title_sort aquaporins: another piece in the osmotic puzzle
publishDate 2012
url http://hdl.handle.net/20.500.12110/paper_00145793_v586_n19_p2991_Alleva
https://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=artiaex&d=paper_00145793_v586_n19_p2991_Alleva_oai
work_keys_str_mv AT allevak aquaporinsanotherpieceintheosmoticpuzzle
AT charao aquaporinsanotherpieceintheosmoticpuzzle
AT amodeog aquaporinsanotherpieceintheosmoticpuzzle
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